Reliability of a uni-compartmental scale for the radiographic evaluation of knee arthritis: data from the multicenter osteoarthritis study

Sheehy, Lisa; Cooke, Tommy; McLean, Linda; Niu, Jingbo; Lynch, J A; Singh, Jasvinder A; Segal, N.A.; Culham, Elsie

doi:10.1016/j.joca.2013.02.420

Cited by 2 publications

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“…CG features of the most severely-affected TF compartment were analyzed [JSN (0-3), presence and size of femoral osteophytes (0-3), presence and degree of tibial attrition (0-4) and evidence of subluxation (0-3)] for a total score from 0-13 (intra-rater reliability: Cohen's weighted kappa 0.65-0.75; test-retest reliability: Cohen's weighted kappa 0.64) 5,18 .…”

Section: 3 Participants and Methodsmentioning

confidence: 99%

Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis Study (MOST)

Sheehy

Culham

McLean

et al. 2015

Osteoarthritis and Cartilage

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Objectives The purpose of this study was to assess the concurrent validity and sensitivity to change of three knee osteoarthritis (OA) grading scales. The Kellgren-Lawrence (KL) and the Osteoarthritis Research Society International (OARSI) joint space narrowing (JSN) grading scales are well-established. The third scale, the compartmental grading scale for OA (CG) is a novel scale which grades JSN, femoral osteophytes, tibial erosion and subluxation to create a total score. Methods One sample of 72 posteroanterior fixed-flexion radiographs displaying mild to moderate knee OA was selected from the Multicenter Osteoarthritis Study to study validity. A second sample of 75 radiograph pairs, which showed an increase in OA severity over 30 months, was selected to study sensitivity to change. The three radiographic grading scales were applied to each radiograph in both samples. Spearman's rank correlation coefficients were used to correlate the radiographic grades and the change in grades over 30 months with a Whole-organ Magnetic Resonance Imaging Score (WORMS)-based composite score which included five articular features of knee OA. Results Correlations between the KL, OARSI JSN and CG grading scales and the MRI-based score were 0.836, 0.840 and 0.773 (p<0.0001) respectively while correlations between change in the radiographic grading scales and change in the MRI-based score were 0.501, 0.525 and 0.492 (p<0.0001). Conclusions All three radiographic grading scales showed high validity and are suitable to assess knee OA severity. They showed moderate sensitivity to change; therefore caution should be taken when using ordinal radiographic grading scales to monitor knee OA over time.

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Section: 3 Participants and Methodsmentioning

confidence: 99%