OBJECTIVE:To compare pulse oximetry oxygen saturation (SpO 2 ) measured by a novel reflectance method from core body to arterial oxygen saturation (SaO 2 ) in neonates and infants. Transmission pulse oximetry (TPO) was measured for comparison.
STUDY DESIGN:We monitored 18 infants by the two pulse oximeters simultaneously. The reflectance pulse oximetry (RPO) (PRO2, ConMed, Utica, NY) was measured on the upper back or chest, while the TPO (N395-Nellcor, Pleasanton, CA) was measured from the finger of the infant on the left hand or feet. Data from the two methods were compared to functional SaO 2 derived from blood sample drawn from arterial line for patient care and measured by a Co-oximeter (Ilex, Instrument Lab. Lexington, MA). The potential advantage of the RPO is demonstrated in a case of a premature infant with hypovolemic shock, where SaO 2 or TPO could not be obtained but oximetry was available from the RPO.
RESULTS:We used for analysis 56 RPO and 32 TPO measurements. SpO 2 obtained from the RPO was 88.3±9.8%, from the TPO 84.2±10.1%, and functional SaO 2 was 88.2±11.7%, with correlation coefficient of 0.93 and 0.88, respectively (p<0.0001). The mean difference (bias) and standard deviation of the differences (precision) between the RPO and the TPO compared to functional SaO 2 were À0.09±4.5% and 1.26±5.9% and the absolute errors were 3.2±3.1%, and 4.4±4.0%, respectively. The accuracy of both RPO and TPO was diminished when SaO 2 was <85%, but only the RPO remained correlated with the functional SaO 2 .CONCLUSIONS: Reflectance pulse oximetry measured from core body of neonates and infants is accurate and reliable and is comparable to the transmission SpO 2 when compared to functional SaO 2 . We speculate that the reflectance method might be advantageous in cases of poor peripheral perfusion in neonates and infants.