Reliability of dual energy X-ray absorptiometry in evaluation of phospho-calcic bioceramics in rabbit

Lu, Jingyu; Legrand, Olivier; Flautre, B.; Gallur, A.; Descamps, M.; Thierry, B.; Hardouin, Pierre; Sutter, B.

doi:10.1016/b978-008042692-1/50092-3

Cited by 1 publication

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“…Lu et al (20) studied porous ceramic (hydroxyapatite and β -tricalcium phosphate with the same porosity measured by mercury intrusion porosimetry) implanted in rabbit femurs and used DXA to evaluate BMD and BMC in the region of interest. DXA allows for the analysis of the implant inside the bone and material modification according to information provided by histomorphometry.…”

Section: Discussionmentioning

confidence: 99%

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Effect of Endodontic Cement on Bone Mineral Density Using Serial Dual-energy X-ray Absorptiometry

Saghiri

Orangi

Tanideh

et al. 2014

Journal of Endodontics

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Introduction Materials with new compositions were tested in order to develop dental materials with better properties. Calcium silicate–based cements, including white mineral trioxide aggregate (WMTA), may improve osteopromotion because of their composition. Nano-modified cements may help researchers produce ideal root-end filling materials. Serial dual-energy x-ray absorptiometry measurement was used to evaluate the effects of particle size and the addition of tricalcium aluminate (C3A) to a type of mineral trioxide aggregate–based cement on bone mineral density and the surrounding tissues in the mandible of rabbits. Methods Forty mature male rabbits (N = 40) were anesthetized, and a bone defect measuring 7 × 1 × 1 mm was created on the semimandible. The rabbits were divided into 2 groups, which were subdivided into 5 subgroups with 4 animals each based on the defect filled by the following: Nano-WMTA (patent application #13/211.880), WMTA (as standard), WMTA without C3A, Nano-WMTA + 2% Nano-C3A (Fujindonjnan Industrial Co, Ltd, Fujindonjnan Xiamen, China), and a control group. Twenty and forty days postoperatively, the animals were sacrificed, and the semimandibles were removed for DXA measurement. Results The Kruskal-Wallis test followed by the Mann-Whitney U test showed significant differences between the groups at a significance level of P < .05. P values calculated by the Kruskal-Wallis test were .002 for bone mineral density at both intervals and P20 day = .004 and P40 day = .005 for bone mineral content. Conclusions This study showed that bone regeneration was enhanced by reducing the particle size (nano-modified) and C3A mixture. This may relate to the existence of an external supply of minerals and a larger surface area of nano-modified material, which may lead to faster release rate of Ca2+, inducing bone formation. Adding Nano-C3A to Nano-WMTA may improve bone regeneration properties.

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Section: Discussionmentioning

confidence: 99%

“…The most common method of measuring bone mass is dual-energy x-ray absorptiometry (DXA), and it is a reliable and noninvasive method (18–20). Surgeons can predict bone health and fracture risk and can measure bone response to osteoporosis treatment by using DXA evaluation.…”

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confidence: 99%