Objective:
To assess trends in PROMIS Physical Function (PF) and Pain Interference (PI) in surgically treated tibial shaft fracture patients progressing to union versus nonunion.
Design:
Retrospective cohort study
Setting:
Level 1 trauma center
Patient Selection Criteria:
Patients with operatively treated tibial shaft fractures (AO/OTA 42-A,B,C) using an intramedullary nail.
Outcome Measures and Comparisons:
PROMIS physical function and pain interference were compared between patients progressing to union and patients requiring nonunion repair.
Results:
A total of 234 patients (196 union, 38 nonunion) were included consisting 144 males and 90 females. The mean age of included patients was 40.8 years. A significant difference in mean PROMIS PF between union and nonunion patients was observed at 1-3 months (p=0.005), 3-6 months (p<0.001), 6-9 months (p=0.003), and 6-12 months (p=0.018). The odds of developing nonunion for every unit decrease in PROMIS PF was significant at 3-6 months (OR 1.07, p=0.028) and 6-9 months (OR 1.17, p=0.015). A significant difference in mean PROMIS PI between union and nonunion patients was observed at 1-3 months (p=0.001), 3-6 months (p=0.005), and 6-9 months (p=0.005). The odds of developing nonunion for every unit increase in PROMIS PI was significant at 1-3 months (OR 1.11, p=0.005), 3-6 months (OR 1.10, p=0.011), and 6-9 months (OR 1.23, p=0.011).
Conclusion:
Poorly trending PROMIS PF and PI in the clinical setting is a factor that can be used to evaluate progression to nonunion following tibial shaft repair where imaging studies may lag behind.
Level of Evidence:
Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.