Reliability of the AMDP‐System A PRELIMINARY REPORT ON A MULTICENTRE EXERCISE ON THE RELIABILITY OF PSYCHOPATHOLOGICAL ASSESSMENT

Busch, H; Cranach, Mario von; Gulbinat, W.; Renfordt, E.; Tegeler, J.

doi:10.1111/j.1600-0447.1980.tb00624.x

Cited by 37 publications

(14 citation statements)

References 2 publications

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“…Compression of morbidity assumes that therapeutic and preventive efforts will compress chronic diseases to a shorter period later in life, resulting in reduced periods of disease (5). In contrast, the expansion of morbidity attributes advances in medicine to decreased fatality rates, thus increasing prevalence rates (5, 7). Dynamic equilibrium, however, suggests that while decreased mortality rates lead to an increase in milder chronic diseases, severe chronic diseases will be reduced, resulting in a better quality of life (6).…”

Section: Introductionmentioning

confidence: 99%

Health-adjusted life expectancy in HIV-positive and HIV-negative men and women in British Columbia, Canada: a population-based observational cohort study

et al. 2017

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Background We sought to understand whether people living with HIV (PLHIV) ever on highly active antiretroviral therapy (HAART) follow a pattern where morbidity is compressed into the last years of life or lessened as people age. Our objective was to estimate Health Adjusted Life Expectancy (HALE) among adults living with and without HIV, and examine dependency between causes of comorbidities. Methods In this retrospective, population-based cohort study, the prevalence of select comorbidities was determined by age and sex using case-finding algorithms. Deaths were obtained from a vital event registry. Comorbid-specific HALE was estimated from 20 years of age by HIV status and sex. For each comorbidity, a healthy state was defined as the proportion of life expectancy comorbid-free, and was adjusted on the probability of occurrence of other different comorbidities. Lastly, the sensitivity of HALE estimates in our study was assessed to the sequencing of select comorbidities for the dependent comorbidity adjustments. Findings Our sample consisted electronic health records from 9,310 HIV-infected and 510,313 uninfected adults over the period 1 April 1996 to 31 December 2012 in British Columbia (BC), Canada. These individuals contributed a total of 49,605 deaths and 5,576,841 person-years over the study period. At exact age 20 years, HALE was approximately 31 years among men living with HIV and 27 years among women living with HIV. In the HIV-negative population, HALE was around 58 years for men and 63 for women. These results appear independent of ordering. However, PLHIV, particularly women living with HIV, had much shorter overall life expectancies than their HIV-negative counterparts in the general population, and thus spent less time in a healthy state. Interpretation While we observed limited differences in the levels of morbidity compression by HIV status, PLHIV – especially women living with HIV – spent less time in a healthy state. Expanded service delivery interventions to address complex care needs of aging PLHIV are critical to addressing shorter life expectancies, and improving their healthy states. Funding Canadian Institutes of Health Research.

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Section: Introductionmentioning

confidence: 99%

Health-adjusted life expectancy in HIV-positive and HIV-negative men and women in British Columbia, Canada: a population-based observational cohort study

et al. 2017

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“…The debate arising from competing hypotheses on compression of morbidity and expansion of morbidity propelled research on health expectancy (Fries, 1980; Gruenberg, 1977; Kramer, 1980). Compression of morbidity posits that seniors live more years free of ill health or disability, with these symptoms appearing at the tail-end of the life expectancy, while expansion of morbidity suggests the gain in life expectancy among the elderly is accompanied by more years lived in ill health and disability.…”

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confidence: 99%

Revisiting Mobility Limitations of Seniors in Singapore, 1995 to 2011

Kang

Yong

Chan

et al. 2016

Gerontology and Geriatric Medicine

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Singapore’s life expectancy at birth and at age 65 continues to improve. Although this is a positive development, it is necessary to understand how much of this increased life expectancy is spent with and without mobility limitations. This research uses the latest round of the National Survey of Senior Citizens to examine the situation in 2011 and the possible changes that may have occurred since the last survey in 2005. It seeks to add to earlier research in this area in Singapore and uses the prevalence-based Sullivan method to calculate lifetime free of mobility limitations for this population. Pertinent conclusions drawn from this research include evidence pointing to changing prevalence rates among the older adult population and observations that suggest the possibility of a compression of morbidity for this population in 2011 compared with an expansion of morbidity observed in the previous survey conducted in 2005. The research also shows that women continue to be disadvantaged as they age compared with men.

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“…To facilitate statistical analysis the clinical variables that contained more than two categories were clustered into two subsets according to Valero et al 24 Briefly, schizophrenia subtypes (on ICD-9 classification) were grouped as positive symptom syndrome-like or negative symptom syndrome-like (the new variable is called 'syndrome subtype') according to the Association for Methodology and Documentation in Psychiatry (AMDP) scale system, 25 which we use in our clinical records. Course of illness was divided into two sets: one containing the episodic subtypes (unique or multiplex) and the other containing the chronic, continuous subtypes.…”

Section: Variables Studiedmentioning

confidence: 99%

Schizophrenic women with the APOE ε4 allele have a worse prognosis than those without it

et al. 2001

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The ⑀4 allele of APOE is generally accepted to be a risk factor in Alzheimer's disease and it has been related to other neuropsychiatric disorders, including schizophrenia. The results of several case-control studies have been inconclusive. To shed more light on this issue we carried out an association study that compared the APOE common variant in a group of 365 schizophrenia patients and 584 controls. We found no differences in the genotype distributions and allele frequencies of patients and controls. In the group of patients, we also analysed the possible influence of the ⑀4 allele in the clinical variables. The most important findings are that the age at onset (AAO) of ⑀4+ schizophrenic women, those that have one or two ⑀4 alleles, is 4 years earlier than that of ⑀4− women and their risk of suffering a negative syndrome subtype is four times greater. This was not found in schizophrenic men. Our results show that the APOE variant is not a risk factor for developing schizophrenia but that it may modulate its phenotypic expression in a sex-dependent manner. Molecular Psychiatry (2001) 6, 307-310.

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Reliability of the AMDP‐System A PRELIMINARY REPORT ON A MULTICENTRE EXERCISE ON THE RELIABILITY OF PSYCHOPATHOLOGICAL ASSESSMENT

Cited by 37 publications

References 2 publications

Health-adjusted life expectancy in HIV-positive and HIV-negative men and women in British Columbia, Canada: a population-based observational cohort study

Health-adjusted life expectancy in HIV-positive and HIV-negative men and women in British Columbia, Canada: a population-based observational cohort study

Revisiting Mobility Limitations of Seniors in Singapore, 1995 to 2011

Schizophrenic women with the APOE ε4 allele have a worse prognosis than those without it

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