This study investigated protective effects of circumcision in a sample of immigrant Latino men who have sex with men (MSM). A survey in Portuguese, Spanish, or English was administered with computer-assisted self-interview technology with audio enhancement (A-CASI) to 482 MSM from Brazil (n = 146), Colombia (n = 169), and the Dominican Republic (n = 167), living in the New York metropolitan area. Logistic regression revealed that after controlling for age, income, education, having had syphilis, having done sex work, and preferring the receptive role in anal intercourse, uncircumcised men were almost twice as likely to be HIV-positive as circumcised men. Follow-up analyses revealed, however, that the protective effects occurred only among the group of Colombian men.
Keywords
HIV; circumcision; MSM; LatinoResearch conducted in areas of Africa with generalized HIV epidemics has provided strong evidence for a protective effect of male circumcision relative to heterosexual HIV infection and has raised the possibility of public health initiatives to promote male circumcision (Williams et al., 2006). Although the extent to which results would be similar in other contexts is not yet clear, the research has potential relevance for other populations in which the epidemic is concentrated (National Institute of Allergy and Infectious Diseases [NIAID], 2006). This study examines circumcision in a population with a high prevalence of HIV in the United States-Latino men who have sex with men (MSM).A link between male circumcision and HIV protection was first supported by observational studies showing lower HIV prevalence in areas of Africa where circumcision was practiced. A meta-analysis of 27 studies found reduced risk of HIV among circumcised men, with even greater effects for men at high risk (Weiss, Quigley, & Hayes, 2000). Marked differences in the magnitude of the effect in different studies, however, suggested that other factors, such as prevalence of ulcerative sexually transmitted infections (STIs), may moderate the degree of risk reduction afforded by circumcision.Three recent randomized control trials conducted in areas of Africa with generalized HIV epidemics have provided stronger evidence that men who are circumcised are less likely to become infected with HIV from their female partners (Auvert et al., 2005;Bailey et al., 2007;Gray et al., 2007). All three studies were terminated early due to the clarity of findings Address correspondence to: Carol A. Reisen, PhD, Department of Psychology, George Washington University, 2125 G Street NW, Washington, DC 20052 (E-mail: creisen@gwu.edu (Auvert et al., 2005;Bailey et al., 2007;Gray et al., 2007). The first study, conducted in Orange Farm Township, South Africa, found a 60% protection from circumcision. Additional analyses that controlled for behavioral factors, such as sexual activity and condom use, resulted in a similar, but slightly higher, estimate (61%). Furthermore, in a study in Rakai, Uganda (Gray et al., 2007), HIV infection was reduced 51% in the...