Reliability, validity and sensitivity of the Chinese (simple) Short Form 36 Health Survey version 2 (SF‐36v2) in patients with chronic hepatitis B

Abstract

SUMMARY. The purpose of the study was to evaluate reliability, validity and sensitivity of the Chinese (simple) SF-36v2 in patients with chronic hepatitis B (CHB). Four hundred and sixty patients were recruited and allocated to CHB (CHB without cirrhosis) (n = 323) and CHB-related cirrhosis (n = 137) groups. Internal consistency reliability was estimated with Cronbach's a-coefficient. Convergent and discriminant validity were assessed by item-scale-component correlation. Factorial validity was explored by principal component factor analysis with varimax rotation. Sensitivity was measured with Cohen's effect size (ES), and independent sample t-test between the CHB and CHBrelated cirrhosis groups and between alanine aminotransferase (ALT) normal and abnormal groups after stratifying illness stages. The results showed that Cronbach's a of the total SF-36v2 was 0.92, with the range from 0.72 to 0.87 in the eight scales and 0.76 to 0.77 in the two summary components. Most of the hypothesized item-scale-component correlations were 0.40 or over, and all of such hypothesized correlations were higher than the alternative ones, indicating satisfactory convergent and discriminant validity. Two and seven factors were extracted after varimax rotation at the scale level and item level. The eligible ES with statistically significant independent sample t-test was found in the physical component summary (PCS) and physical function (PF), role-physical (RP), general health (GH), vitality (VT), social functioning (SF) scales by comparison between CHB and CHB-related cirrhosis groups, and in the PCS and PF, GH, SF scales by comparison between the ALT normal and abnormal groups in the stratification of patients with CHB. In conclusion, the Chinese (simple) SF-36v2 has acceptable reliability, validity and sensitivity in patients with CHB.

Reliability, validity and responsiveness of the short form-36 health survey: Findings from the women's health study of Accra, Ghana

“…Item divergence showed that all items successfully discriminated between their hypothesized scale and other measuring constructs. These findings compare favourably to previous studies conducted in, Lebanon (Sabbah et al, 2003), China (Qu et al, 2009;Zhou et al, 2013;Zhang et al, 2012) and other developed countries (Ware, Gandek, 1998a) using the SF-36. Item convergence was achieved for all with the exception of «feeling tired».…”

Significant impairment of health-related quality of life in mainland Chinese patients with chronic hepatitis B: a cross-sectional survey with pair-matched healthy controls

“…The eight domains are aggregated into two summary measures: physical component summary (PCS) and mental component summary (MCS). The standard (4-week recall) Chinese (mainland) form was provided by QualityMetric Incorporated, which has been validated in mainland Chinese CHB patients [16]. We scored all domains and summaries as norm-based scores which have the same general population mean of 50 and standard deviation of 10.…”

Development of a Diagnostic Questionnaire for Damp Phlegm Pattern and Blood Stasis Pattern in Coronary Heart Disease Patients (CHD-DPBSPQ)

“…e correlations of the CHD-DPBSPQ between the phlegm domain and our hypothesized components (chest distress, sleepiness, physical heaviness, obesity, sticky mouth, abdominal fullness, anorexia, greasy tongue fur, and slippery pulse) were greater than 0.4, as were the correlations of the CHD-DPBSPQ between the blood stasis domain and our hypothesized components (chest pain, cyanotic lips, dim complexion, dark purple tongue, petechiae or ecchymosis on the tongue, and sublingual vein cyanosis), indicating moderate convergence validity [48]. In short, these findings are encouraging and support the structural integrity of the CHD-DPBSPQ.…”

“…e root mean square error of approximation (RMSEA) was 0.05, indicating that the fit was close to good [47]. e correlation coefficients of the subscales and items were equal to or greater than 0.4, suggesting good convergence validity [48].…”