Relief of Cardiorespiratory Symptoms and Increased Physical Activity After Surgically Induced Weight Loss

Karason, Kristjan; Lindroos, Anna Karin; Stenlöf, Kaj; Sjöström, Lars

doi:10.1001/archinte.160.12.1797

Cited by 156 publications

(136 citation statements)

References 40 publications

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“…It has been demonstrated that weight reduction improves functional health, for example, surgically induced weight loss is associated with a marked relief in dyspnea and chest pain. 25,26 However, symptoms like these could also be interpreted as reactions to underlying mental stress, predisposing a life-style causing obesity, and consequently amplify the condition specific problems.…”

Section: Discussionmentioning

confidence: 99%

Severe obesity and personality: a comparative controlled study of personality traits

et al. 2003

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OBJECTIVE:The primary purpose was to assess personality trait differences between the severely obese seeking treatment and a mainly non-obese reference group. We also investigated gender differences and differences between obese patients and obese not seeking treatment. METHOD: Personality traits were assessed using 7 of 15 scales from the Karolinska Scales of Personality (KSP): Somatic Anxiety, Muscular Tension, Psychastenia, Psychic Anxiety, Monotony Avoidance, Impulsiveness, and Irritability. Patients from the Swedish Obese Subjects (SOS) intervention study (n ¼ 3270, ages 37-57, 71% women) and the SOS reference study (n ¼ 1135, 54% women) completed the survey. Data presented in this study were gathered prior to treatment. Significance tests and effects sizes were calculated. RESULTS: Although statistically significant differences were found between obese patients and reference subjects on nearly all personality traits, effect sizes were at most moderate. Of the three scales with moderate effects sizes, differences on Somatic Anxiety and Psychastenia could be traced to items tapping condition-specific symptoms, e.g., problems with sweating and breathing as indicators of Somatic Anxiety. Moderate differences on the Impulsiveness scale (men alone) could not be explained by item composition. Further, the obese patients differed from obese in the reference group, and both obese and reference women reported significantly higher levels on Somatic Anxiety, Muscular Tension and Psychic Anxiety compared to men (effect size: small). CONCLUSIONS: Our results provided no evidence of a general obese personality profile, instead considerable heterogeneity in personality traits was observed across our obese samples (treatment seekers vs non-seekers, men vs women) and generally only small differences were noted compared to a reference study population. Further research is needed to investigate if the somewhat elevated levels of Impulsiveness, particularly among male obese patients, is affected by weight loss. When assessing personality traits in diseased groups consideration should be given to possible confounding from, e.g., somatic symptoms.

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Section: Discussionmentioning

confidence: 99%

Severe obesity and personality: a comparative controlled study of personality traits

et al. 2003

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“…With BMI ≥ 40 kg/m 2 (EL A, B, C [14,[19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] 3. BMI criterion may be the current BMI or previously maximum attained BMI of this severity.…”

Section: Indications For Bariatric Surgerymentioning

confidence: 99%

Interdisciplinary European Guidelines on Metabolic and Bariatric Surgery

et al. 2013

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In 2012, an outstanding expert panel derived from IFSO-EC (International Federation for the Surgery of Obesity -European Chapter) and EASO (European Association for the Study of Obesity), composed by key representatives of both Societies including past and present presidents together with EASO's OMTF (Obesity Management Task Force) chair, agreed to devote the joint Medico-Surgical Workshop of both institutions to the topic of metabolic surgery as a pre-satellite of the 2013 European Congress on Obesity (ECO) to be held in Liverpool given the extraordinarily advancement made specifically in this field during the past years. It was further agreed to revise and update the 2008 Interdisciplinary European Guidelines on Surgery of Severe Obesity produced in cooperation of both Societies by focusing in particular on the evidence gathered in relation to the effects on diabetes during this lustrum and the subsequent changes that have taken place in patient eligibility criteria. The expert panel composition allowed the coverage of key disciplines in the comprehensive management of obesity and obesity-associated diseases, aimed specifically at updating the clinical guidelines to reflect current knowledge, expertise and evidence-based data on metabolic and bariatric surgery.

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“…The Swedish Obese Subjects (SOS) study with gastric surgery showed a dose-response between weight loss and CVD risk factors, including blood pressure, cholesterol, HDL, uric acid, and blood glucose at 2 years. Lipid benefit required a 30-kg weight loss in this very obese group, although lesser degrees of weight loss benefited the other risk factors (19). In the University Group Diabetes Program (UGDP) study, comparison of placebo with insulin treatment showed no change in mortality, perhaps in part because only the former group showed sustained weight loss.…”

Section: Diagnosis Of Cvdmentioning

confidence: 92%

“…Emoto et al (abstract 554) reported that plasma total homocysteine was associated with ultrasonographic intimal-medial thickness of the carotid and femoral arteries in 81 individuals with type 2 diabetes and 127 healthy control subjects. Hosoi et al (abstract 219) reported that a common mutation in the enzyme methylenetetrahydrofolate reductase, which is involved in the folate-dependent remethylation of homocysteine to methionine, determining plasma homocysteine levels, was associated with an increased level of coronary 19 and 63. Adipose tissue tumor necrosis factor (TNF) mRNA and, to a greater extent, TNF secretion increased with increasing obesity and with increasing insulin resistance, although there was no change in plasma TNF.…”

Section: Cvd Abstractsmentioning

confidence: 99%