We r evi ew ed data fr om appr oxi matel y 80 publ i shed and unpubl i shed studi es that exami ned the association of religious affiliation or involvement with depressi ve symptoms or depr essi ve di sor der. I n these studi es, r el i gi on w as measur ed as r el i gi ous affiliation; general religious involvement; organizational religious involvement; prayer or private religious involvement; religious salience and motivation; or religious beliefs. People from some religious affiliations appear to have an el evated r i sk for depr essi ve symptoms and depr essi ve di sor der, and peopl e w i th no religious affiliation are at an elevated risk in comparison with people who are religiously affiliated. People with high levels of general religious involvement, organizational religious involvement, religious salience, and intrinsic religious motivation are at reduced risk for depr essi ve symptoms and depr essi ve di sor der s. Pr i vate r el i gi ous acti vi ty and par ti cul ar r el i gi ous bel i efs appear to bear no r el i abl e r el ati onshi p w i th depr essi on. Peopl e w i th hi gh l evel s of extr i nsi c r el i gi ous moti vati on ar e at i ncr eased r i sk for depr essi ve symptoms. A l though these associ ati ons tend to be consi stent, they ar e modest and ar e substanti al l y r educed i n mul ti var i ate r esear ch. Longi tudi nal r esear ch i s spar se, but suggests that some for ms of r el i gi ous i nvol vement mi ght exer t a pr otecti ve effect agai nst the i nci dence and per si stence of depr essi ve symptoms or di sor der s. The exi sti ng r esear ch i s suffi ci ent to encour age fur ther i nvesti gati on of the associ ati ons of r el i gi on w i th depr essi ve symptoms and di sor der. Rel i gi on shoul d be measur ed w i th hi gher methodol ogi cal standar ds than those that have been accepted i n sur vey r esear ch to date. Keyw or ds: rel i gi on, rel i gi ous i nvol vement, psychi atri c epi demi ol ogy, depressi on, depressi ve di sorder, affecti ve di stress, measurement, psychometri cs Depressi on i s one of the most common mental di sorders. Wi thi n thei r l i feti me, betw een 10 and 25% of w omen and 5-12% of men will meet the cri teri a for major depressi ve di sorder, w hi l e at any gi ven poi nt i n ti me betw een 5 and 12% of w omen and 2-3% of men meet the cri teri a for major depressi ve di sorder.1 Depressi on i s expensi ve fi nanci al l y and i n terms of human l i fe. It appears that medi cal care for depressi on i s on the ri se. Pi ncus et al 2 revi ew evi dence i ndi cati ng that vi si ts to physi ci ans for depressi on i ncreased from 11 million in 1985 to 20.4 million in 1993-1994, and vi si ts that i ncl uded treatment w i th an anti depressant medi cati on i ncreased from 5.3 million to 12.4 million in the same ti me frame. In addi ti on, peopl e w i th major depressi on have a substanti al l y i ncreased ri sk for use of hospi tal and medi cal servi ces, sui ci de attempts, and earl y death.
3Rel i gi on i s a vari abl e that i s not commonl y di scussed i n...