Remaining useful life (RUL) is the premise and basis of the equipment health management plan. As accurate as possible life prediction is of great significance to reliability and economy of equipment maintenance. In this paper, a data-driven improved particle filter (PF) RUL prediction method is proposed. A health indicator extraction method based on multi-feature fusion is introduced for the RUL prediction, which can visually show the degradation trend of the healthy state of the equipment. The degradation model and observation model of equipment health indicators are established, and the PF algorithm is used to track parameters of the model. A quantum genetic algorithm is employed to improve the problem of particle degradation in PF. On the basis of filter tracking, long short term memory (LSTM) network is used to predict the trend of model coefficients, which further improves the accuracy of RUL prediction. The experiment using the C-MAPSS data set shows the proposed method has a better prediction accuracy than other methods. INDEX TERMS Remaining useful life, particle filter, quantum genetic algorithm, long short term memory.