2019
DOI: 10.1080/10428194.2019.1612063
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Remission of acquired von Willebrand syndrome in a patient with chronic lymphocytic leukemia treated with venetoclax

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Cited by 4 publications
(9 citation statements)
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“…Prompt substitutive/anti-coagulant therapy is usually required, and a delay may be fatal. Generally, AH and VWS may respond to CLL therapy including rituximab and venetoclax, whilst the use of ibrutinib is discouraged due to bleeding risk [31,42,43].…”
Section: Aid In Cllmentioning
confidence: 99%
“…Prompt substitutive/anti-coagulant therapy is usually required, and a delay may be fatal. Generally, AH and VWS may respond to CLL therapy including rituximab and venetoclax, whilst the use of ibrutinib is discouraged due to bleeding risk [31,42,43].…”
Section: Aid In Cllmentioning
confidence: 99%
“…The immunochemotherapy used in some disseminated indolent lymphomas, such as bendamustine‐rituximab, CVP‐rituximab and CHOP‐rituximab was associated with AWS‐ORRs of 66.7% (4/6) 44–49 , 66.7% (2/3) 50,51 and 75% (3/4), respectively 44,46,52,53 . Older drugs, such as chlorambucil, provided an AWS‐ORR of 50% (2/4), 14,54,55 and more recent drugs, such as, showed an AWS‐ORR of 75% (3/4),47 , 51 including one inefficient combination with rituximab 47 . Several regimens were only used once in various diseases.…”
Section: Resultsmentioning
confidence: 96%
“…The most important point is that the AWS‐ORR also matched the LRD‐R for most lines of treatment (43 patients, 55 lines of treatment). The median and mean times to normalise VWF levels in LRD were 4.75 and 7.6 months (.2–24 months), respectively 15,40,42,46–48,51–53,55–57 . Several cases described an improvement of bleeding syndrome prior to the biological improvement of AWS 48,51 …”
Section: Resultsmentioning
confidence: 99%
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