Remission of myasthenia gravis following cervical adjustment

Abstract

Myasthenia gravis (MG) is an autoimmune disorder, caused by circulating antibodies against the acetylcholine receptor (AChR) and associated proteins. Anticholinesterase medications and immunomodulating therapies are the mainstays of current treatment. Presented here is a case of a 51-yearold female who had been diagnosed with MG based on symptoms and continued elevation of antibody to AChR (anti-AChR) by her family physician. The patient's anticholinesterase medication was halted due to significant side effects affecting bowel function. She only received acupuncture treatment in the past 4 months prior to this presentation. Myasthenic symptoms deteriorated and the anti-AChR titer kept elevating after stopping medication. She originally came to us due to neck and back pain rather than myasthenic complaints. This case is interesting that her back pain and myasthenic symptoms went into complete remission within 1 month of initiating chiropractic adjustment. The concomitant recession of the myasthenic symptoms raises considerable interest for the mystery of MG, including the causal link between stress and autoimmune disease, the role of ACh in immune regulation, and the possible mechanisms of disease amelioration. Further studies would shed more light on the efficacy of various modalities in treating MG.

Remission of recalcitrant dermatomyositis following a chiropractic adjustment

“…[9] We speculate that cervical manipulations unintendedly trigger the baroreceptors of the carotid sinus, leading to an interaction between vagus nerve stimulation and cholinergic anti-inflammatory reaction. [10] Moreover, manipulative treatment can help patients stretch the muscles and tendons, release nerve root compression, regain joint function, and prevent muscle atrophy. The therapeutic goal is to maintain function and prevent or minimize sequelae.…”

Vertebral Subluxation and Systems Biology: An Integrative Review Exploring the Salutogenic Influence of Chiropractic Care on the Neuroendocrine-Immune System

“…Similarly, another trial details an increase in antibody secretion from cells isolated from subjects undergoing spinal manipulation, as compared to sham control [ 93 ]. The present search also identified a number of case studies with quantitative evidence of functional improvement of autoimmune and infectious processes, such as the resolution of chronic and/or treatment-recalcitrant idiopathic arthritis, asthma, otitis media, and myasthenia gravis following the introduction of chiropractic care [ 123 , 128 , 131 , 134 , 136 , 140 , 143 ], and/or report of reduced frequency of illness or school misses after commencement of chiropractic care [ 133 , 142 , 144 , 145 , 152 ]. Together, these original data are supportive of chiropractic care impacting immune adaptability in an evident model of practice.…”

The Inclusion of Chiropractic Care in the Healthy China Initiative 2030

“…Second, the government should promote research on the clinical efficacy and costeffectiveness of chiropractic care in the Chinese context. This can involve collaborations between Chinese researchers and their international counterparts who are experienced in chiropractic research [6,[32][33][34][35].…”