Remission of obsessive-compulsive disorders and syndromes; evidence from a prospective community cohort study over 30 years

Fineberg, Naomi; Hengartner, Michael Pascal; Bergbaum, Carmel; Gale, Tim M.; Rössler, Wulf; Angst, Jules

doi:10.3109/13651501.2013.777744

Cited by 51 publications

(33 citation statements)

References 37 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, there were numerous confounds to the study by Tolin et al (2010), including a dearth of older adults in the study sample, a lack of verification of hoarding status, and no differentiation in the type of hoarding symptom (e.g., saving, difficulty discarding, or clutter). Most important, the course of symptoms was not waxing and waning as seen in the trajectory of other mental health disorders across the lifespan, such as in OCD (Fineberg et al, 2013;Ravizza, Maina, & Bogetto, 1997;Skoog & Skoog, 1999) and in mood disorders (Coryell, Endicott, & Keller, 1990;Coryell et al, 1994;Richards, 2011). However, this may also be the result of our use of retrospective instead of longitudinal analyses.…”

Section: Discussionmentioning

confidence: 91%

Age of onset and progression of hoarding symptoms in older adults with hoarding disorder

Dozier

Porter

Ayers

2015

Aging & Mental Health

View full text Add to dashboard Cite

Objectives-We investigated (1) age of onset of hoarding disorder (HD) symptoms and diagnosis, (2) late-onset HD, (3) progression of HD symptoms, and (4) association between demographics and hoarding progression.Method-Eighty-two older adults with HD provided retrospective ratings of their hoarding symptoms for each decade of life. Age of onset of symptoms (saving, difficulty discarding, and clutter) was operationalized as the first decade in which the participant reported at least minor symptom severity, and age of onset for possible HD diagnosis was operationalized as the first decade in which the participant reported all three symptoms. We used mixed effects modeling to examine the progression of HD symptoms.Results-The median age of onset for symptoms was between 10 and 20 years, and the median age of onset for possible HD diagnosis was between 20 and 30 years. Twenty-three percent of participants reported onset of possible HD diagnosis after the age of 40. All HD symptoms increased in severity over time. Men reported higher initial clutter and a slower increase in hoarding severity for all symptoms. Increased education was associated with slower increase in saving. Having at least one parent with hoarding tendencies was associated with higher initial hoarding symptoms.Conclusion-Generally, symptoms of HD begin relatively early and worsen across the lifespan. However, approximately one fourth of older adults with HD reported a possible onset after the age of 40.

show abstract

Section: Discussionmentioning

confidence: 91%

Age of onset and progression of hoarding symptoms in older adults with hoarding disorder

Dozier

Porter

Ayers

2015

Aging & Mental Health

View full text Add to dashboard Cite

show abstract

“…In OCD, most longitudinal studies have reported on clinical cohorts (33–36), although one population-based longitudinal cohort study has been performed in adults (37), with follow-up periods ranging between 3 and 40 years. Some of these studies suggest that OCD has a relatively stable and chronic course, while others report more favorable outcomes with age (33–36).…”

Section: Objectivesmentioning

confidence: 99%

Age-Specific Prevalence of Hoarding and Obsessive Compulsive Disorder: A Population-Based Study

Cath

Nizar

Boomsma

et al. 2017

The American Journal of Geriatric Psychiatry

109

View full text Add to dashboard Cite

Objectives Little is known about the age-specific prevalence of hoarding and obsessive compulsive (OC) symptoms, particularly in older age groups. The objectives of this study were to estimate the age-specific prevalence, severity and relationships between hoarding and OC symptoms in males and females using a large population-based sample. Methods We assessed the age-specific prevalence rates of hoarding disorder (HD) and obsessive compulsive disorder (OCD) in males and females (at various age ranges between 15–97 years) from the Netherlands Twins Register; n=15,194. Provisional HD and OCD diagnoses were made according to DSM-5 criteria utilizing self-report measures. We also assessed hoarding and OC symptom severity in the various age groups, and explored specific hoarding and OC symptom patterns (e.g., difficulty discarding, excessive acquisition, clutter, checking, washing, perfectionism and obsessions) with age. Results Prevalence of provisional HD diagnoses (2.12%) increased linearly by 20% with every 5 years of age (z = 13.8, p < 0.0001) and did not differ between males and females. Provisional OCD diagnoses were most common in younger individuals and in individuals over age 65. Co-occurring OCD increased hoarding symptom severity (coefficient = 4.5, SE = 0.2, 95% CI = 4.1 to 4.9, t=22.0, p<0.0001). Difficulty discarding for HD and checking behaviors for OCD appeared to drive most of the increase in these diagnoses in older ages. Conclusions Increased prevalence and severity of HD with age appears to be primarily driven by difficulties with discarding. Increases in OCD prevalence with older age were unexpected, and of potential clinical relevance.

show abstract

“…However, a recent epidemiological study suggests that approximately 50% of community-based cases followed up for approximately 30 years appear to have achieved remission by the age of 50 years, noting that only a minority (40%) sought professional treatment for their OCD (Fineberg et al, 2013b). More severe illness and a longer duration of illness were both associated with a lower likelihood of remission, highlighting the importance of early detection and treatment (Marcks et al, 2011;Eisen et al, 2013;Fineberg et al, 2013b). In the recent, prospective longitudinal study by Eisen et al (2013), participants with primary obsessions were more likely to experience a remission, whereas those with primary hoarding were less likely to remit, and over half of the participants who remitted subsequently relapsed.…”

Section: Relapse Prevention (Continuation and Maintenance Treatment)mentioning

confidence: 95%

Obsessive–compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults

Fineberg

Reghunandanan

Simpson

et al. 2015

Psychiatry Research

Self Cite

114

View full text Add to dashboard Cite

Remission of obsessive-compulsive disorders and syndromes; evidence from a prospective community cohort study over 30 years

Abstract: Our findings suggest a lack of diagnostic stability over the long-term and a high chance of eventual remission, albeit often after several years of illness, for obsessive-compulsive syndromes including OCD. However, roughly one-third of OCD cases do not remit by 50 years of age.

Cited by 51 publications

References 37 publications

Age of onset and progression of hoarding symptoms in older adults with hoarding disorder

Age of onset and progression of hoarding symptoms in older adults with hoarding disorder

Age-Specific Prevalence of Hoarding and Obsessive Compulsive Disorder: A Population-Based Study

Obsessive–compulsive disorder (OCD): Practical strategies for pharmacological and somatic treatment in adults

Contact Info

Product

Resources

About