Remission Rates in Breast Cancer Treated with Preoperative Chemotherapy and Radiotherapy

Abstract

Combination of neoadjuvant chemo-/radiotherapy results in significantly higher rates of complete remission than neoadjuvant chemotherapy alone. The significance for tumor-free and overall survival has to be evaluated.

Prediction of Axillary Lymph Node Status of Breast Cancer Patients by Tumorbiological Factors of the Primary Tumor

“…The need for axillary lymph node dissection is challenged by these facts, since side effects of breast cancer surgery are mainly related to axillary lymph node dissection [1]. Moreover, an increasing number of patients is treated by neoadjuvant chemotherapy [16]. In these patients the role of axillary lymph node dissection for prognosis and locoregional control of the tumor is also uncertain [16].…”

Internal Mammary Nodes in Invasive Breast Carcinoma

“…Significant controversy surrounds targeting of the IMNs with RT [1,2,4,6,8,9,12,13,18,19,24,25,[28][29][30][31][32][33]. Recent analysis of patients treated in the Danish randomized trials who received RT to the chest wall and regional lymphatics including IMNs did not show an adverse effect on cardiovascu- [14].…”

Retrospective Study of Neoadjuvant Versus Adjuvant Radiochemotherapy in Locally Advanced Noninflammatory Breast Cancer

“…Local hyperthermia was delivered with 43.5-44.5 °C over 60 min immediately before interstitial radiotherapy. Details of treatment have been described previously [1,15,16]. 214 neoadjuvant patients (82/100 patients with cT1-T2 tumors, 84/137 patients with cT3 tumors, and 48/78 patients with cT4 tumors) received only an electron boost after external-beam radiotherapy and no interstitial boost.…”