Remodelling in atrial fibrillation: the impact of amiodarone

Grosu, Alin; Rădulescu, Dan; Grosu, L; Pop, Dana

doi:10.5830/cvja-2019-012

Cited by 6 publications

(10 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 6 At three months following surgery, the ablation line can scar and form an absolute barrier, which can interrupt the feedback pathway, reduce the AF recurrence rate, and increase the conversion rate to sinus rhythm. 7 Studies have found that postoperative amiodarone for at least three months can impact on the rhythm instability caused by the postoperative inflammation and thereby reduce the risk of AF recurrence; 8 (2) it could be inferred from Table 6 that in the early postoperative period, the LAD was significantly reduced in both groups of patients compared with pre-operation data. The LAD further reduced during the midterm postoperative period.…”

Section: Discussionmentioning

confidence: 99%

Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease

Jiang¹,

Gu²,

Song³

et al. 2021

IJGM

View full text Add to dashboard Cite

To investigate the therapeutic effects of a modified simultaneous unipolar salineirrigated radiofrequency ablation by intracardiac operation under direct vision in patients with mitral valve diseases combined with atrial fibrillation (AF). Methods: A total of 168 patients with mitral valve diseases combined with AF who underwent unipolar saline-irrigated radiofrequency ablation modified maze procedures were enrolled and divided into the mitral stenosis (MS) group (n = 87) and the mitral insufficiency (MI) group (n = 81). Results: Those with a left atrium diameter (LAD) < 55 mm had a better cardioversion effect during the mid-term post-operation than those with a LAD ≥ 55 mm (P < 0.05). The cardioversion effect during the mid-term post-operation was better in those with a duration of AF < 2 years than those with AF ≥ 2 years (P < 0.05). The LAD reduced significantly during the early postoperative period in the MS group (P < 0.05). Compared with the early postoperative period, LAD further reduced, and the EF increased significantly during the mid-term post-operation (P<0.05). The LAD reduced significantly during the early postoperative period in the MI group (P < 0.05), together with relatively decreased EF (P < 0.05). Compared with the early postoperative period, LAD further reduced, and the EF increased significantly during the mid-term post-operation (P<0.05). The improvement of LAD in the MI group during the mid-term postoperation was better than that in the MS group (P < 0.05). Conclusion:The cardioversion effects and the improvement in cardiac function during the mid-term post-operation were good in the radiofrequency ablation by intracardiac operation under direct vision in patients with different mitral valve diseases combined with AF. The cardioversion effects during the early postoperative period and the mid-term post-operation were better in patients with MI than in those with MS.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease

Jiang¹,

Gu²,

Song³

et al. 2021

IJGM

View full text Add to dashboard Cite

show abstract

“…In patients in whom sinus rhythm has been restored, the same drugs used for cardioversion may be used to prevent arrhythmia relapses. Among these drugs, amiodarone has been shown to be the most effective antiarrhythmic, though not without long term side effects [16].…”

Section: Atrial Fibrillation (Fa) Cardioversion and Anticoagulationmentioning

confidence: 99%

“…As more findings emerge from clinical studies and real-world evidence, the use of NOACs is becoming increasingly varied, replacing VKAs therapy in many contexts as a safe, reliable and effective therapeutic approach [9,12,16,17,18,21,43]. However, VKAs still play an important role in countless contexts, including situations where NOACs are contraindicated [36].…”

Section: Novel Oral Anticoagulants (Noacs): a Future Already Presentmentioning

confidence: 99%

Atrial Fibrillation and Stroke. A Review on the Use of Vitamin K Antagonists and Novel Oral Anticoagulants

2019

View full text Add to dashboard Cite

Atrial fibrillation (AF) is the most common arrhythmia, ranging from 0.1% in patients <55 years to >9% in octogenarian patients. One important issue is represented by the 5-fold increased ischemic stroke risk in AF patients. Hence, the role of anticoagulation is central. Until a few years ago, vitamin K antagonists (VKAs) and low molecular weight heparin represented the only option to prevent thromboembolisms, though with risks. Novel oral anticoagulants (NOACs) have radically changed the management of AF patients, improving both life expectancy and life quality. This review aims to summarize the most recent literature on the use of VKAs and NOACs in AF, in light of the new findings.

show abstract

“…Atrial fibrillation (AF) is the most common cardiac arrhythmia [1][2][3][4][5]. With increasing life expectancy, the incidence and prevalence of AF continue to rise with an estimated worldwide prevalence of 46.3 million.…”

Section: Introductionmentioning

confidence: 99%

“…Rhythm control, which involves antiarrhythmic drugs (AADs), cardioversion (chemical or electrical), or ablation to maintain sinus rhythm (SR), is considered to be a second-line treatment for AF. When rhythm control is chosen, catheter ablation (CA) for AF is considered as a second-line treatment after failure of at least one AAD or intolerance [5][6][7]. Regardless of which approach is pursued, both require risk factors and stroke risk reduction evaluation.…”

Section: Introductionmentioning

confidence: 99%

Cardiovascular Outcomes With an Early Rhythm Control Strategy in Atrial Fibrillation: A Systematic Review

et al. 2022

View full text Add to dashboard Cite

In practice, atrial fibrillation (AF) is typically managed by controlling ventricular rate given similar long-term outcomes and a more tolerable drug profile when compared to rhythm control. However, despite treatment via rate control, patients remain at increased risk for cardiovascular complications. This systematic review provides a summary of literature evaluating the effectiveness of early rhythm control (ERC, initiated within 2 years of diagnosis) in AF in reducing cardiovascular complications. A systematic review utilizing the MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews was performed to identify literature evaluating effectiveness of rhythm control strategies and cardiovascular complication reduction rates in ERC. A total of three literature articles meeting the inclusion and exclusion criteria were included for evaluating the benefit of ERC. One of these examined was a trial that directly compared antiarrhythmic drug (AAD) versus catheter ablation (CA) therapy in maintenance of sinus rhythm (SR). This systematic review shows that ERC is associated with a reduction of cardiovascular events in AF patients compared to other treatment strategies.

show abstract

Remodelling in atrial fibrillation: the impact of amiodarone

Cited by 6 publications

References 54 publications

Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease

Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease

Atrial Fibrillation and Stroke. A Review on the Use of Vitamin K Antagonists and Novel Oral Anticoagulants

Cardiovascular Outcomes With an Early Rhythm Control Strategy in Atrial Fibrillation: A Systematic Review

Contact Info

Product

Resources

About