Remote effects in the ipsilateral thalamus and/or contralateral cerebellar hemisphere using FDG PET in patients with brain tumors

Iwasa, Hitomi; Murata, Yoriko; Nishimori, Miki; Miyatake, Kana; Tadokoro, M.; Kohsaki, Shino; Nogami, Munenobu; Ueba, Yusuke; Ueba, Tetsuya; Yamagami, Takuji

doi:10.1007/s11604-018-0721-8

Cited by 3 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…confirmed that reduced 2-deoxy-2-[fluorine-18]-fluorodeoxyglucose uptake in the ipsilateral thalamus was observed in 21% of the patients with brain tumors, and a simultaneous reduction in cortical metabolism around the tumor was observed in 70% of the patients. [ 8 ] The meningioma in our patient may have had a similar remote effect, which would explain our aforementioned 123 I-IMP SPECT findings.…”

Section: Discussionmentioning

confidence: 59%

“…Similar to these cases, localized brain lesions are known to cause neurological impairments in remote sites (a “remote effect”). [ 8 ] Iwasa et al . confirmed that reduced 2-deoxy-2-[fluorine-18]-fluorodeoxyglucose uptake in the ipsilateral thalamus was observed in 21% of the patients with brain tumors, and a simultaneous reduction in cortical metabolism around the tumor was observed in 70% of the patients.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Hemichorea induced by a sphenoid ridge meningioma

Inoue

Yamamura²,

Yamada

et al. 2021

Surgical Neurology International

View full text Add to dashboard Cite

Background: Movement disorders are rare in brain tumors. We describe a 45-year-old woman with hemichorea, a concomitant contralateral sphenoid ridge meningioma. Case Description: The meningioma enlarged as her hemichorea worsened, and after meningioma resection, the hemichorea gradually subsided. N-isopropyl-p-[123I]-iodoamphetamine single-photon emission computed tomography performed preoperatively showed decreased regional cerebral blood flow (CBF) to the basal ganglia circuit ipsilateral to the tumor and, when repeated postoperatively, confirmed improved regional CBF. Conclusion: We propose that the enlarging sphenoid ridge meningioma had a remote effect on regional CBF and the thalamocortical motor center and that complex changes in the basal ganglia output may have caused the hemichorea.

show abstract

Section: Discussionmentioning

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Hemichorea induced by a sphenoid ridge meningioma

Inoue

Yamamura²,

Yamada

et al. 2021

Surgical Neurology International

View full text Add to dashboard Cite

show abstract

PET and SPECT imaging of the brain: a review on the current status of nuclear medicine in Japan

Kaneta

2020

Jpn J Radiol

View full text Add to dashboard Cite

EMATA: a toolbox for the automatic extraction and modeling of arterial inputs for tracer kinetic analysis in [18F]FDG brain studies

De Francisci,

Silvestri,

Bettinelli

et al. 2024

EJNMMI Phys

View full text Add to dashboard Cite

Purpose PET imaging is a pivotal tool for biomarker research aimed at personalized medicine. Leveraging the quantitative nature of PET requires knowledge of plasma radiotracer concentration. Typically, the arterial input function (AIF) is obtained through arterial cannulation, an invasive and technically demanding procedure. A less invasive alternative, especially for [ 18 F]FDG, is the image-derived input function (IDIF), which, however, often requires correction for partial volume effect (PVE), usually performed via venous blood samples. The aim of this paper is to present EMATA: Extraction and Modeling of Arterial inputs for Tracer kinetic Analysis, an open-source MATLAB toolbox. EMATA automates IDIF extraction from [ 18 F]FDG brain PET images and additionally includes a PVE correction procedure that does not require any blood sampling. Methods To assess the toolbox generalizability and present example outputs, EMATA was applied to brain [ 18 F]FDG dynamic data of 80 subjects, extracted from two distinct datasets (40 healthy controls, 40 glioma patients). Additionally, to compare with the reference standard, quantification using both IDIF and AIF was carried out on a third open-access dataset of 18 healthy individuals. Results EMATA consistently performs IDIF extraction across all datasets, despite differences in scanners and acquisition protocols. Remarkably high agreement is observed when comparing Patlak’s K i between IDIF and AIF (R 2 : 0.98 ± 0.02). Conclusion EMATA proved adaptability to different datasets characteristics and the ability to provide arterial input functions that can be used for reliable PET quantitative analysis. Supplementary Information The online version contains supplementary material available at 10.1186/s40658-024-00707-2.

show abstract

Remote effects in the ipsilateral thalamus and/or contralateral cerebellar hemisphere using FDG PET in patients with brain tumors

Abstract: Reduced FDG uptake in ipsilateral TH and contralateral CE usually occur simultaneously in patients with solitary brain tumors.

Cited by 3 publications

References 25 publications

Hemichorea induced by a sphenoid ridge meningioma

Hemichorea induced by a sphenoid ridge meningioma

PET and SPECT imaging of the brain: a review on the current status of nuclear medicine in Japan

EMATA: a toolbox for the automatic extraction and modeling of arterial inputs for tracer kinetic analysis in [18F]FDG brain studies

Contact Info

Product

Resources

About