Mass movements or mass wasting is being considered as one of the severe forms of natural disasters. Iran is geographically located in the Alps-Himalaya seismicity belt. It has a high potential to mass wasting. This seismic phenomenon creates landslides and rock falls in the high mountains of Alborz and Zagros. These mass movements and various types of slides can be systematically assessed and mapped through traditional mapping frameworks using geoinformation technologies. The geo-information-based technology offers the earth scientist to study and map various types of mass movement and stability of slopes. In this study, we used field data coupling with the tectonic-related factors to provide a solution for slope-related hazards. Firstly, various geological and geomorphological factors such as lineaments and faults, vegetation, lithology, slope, drainage, land use/land cover, seismicity and roads network were extracted and compiled using geo-information technology. This is because the factors mentioned above play important role in the instability of the region. Then, the study area was divided into four regions based on the rate of mass wasting and its degree of vulnerability. The results of this study showed that the erosion in Karaj formation is severe. Additionally, this research also reveals that the hydrothermal solutions caused by the erosional activities have influenced the glassy element of tuffs and subsequently changed into the clays. This change has caused the tuffs to be relatively unstable. Further, it is evident that the chemical and physical weathering has had a big impact on it whilst most of the mass wasting has occurred within the unstable tuffs of Karaj formation. Finally, the paper concluded that the recent construction of the new roads in the region has increased the potential danger for generating the mass wastes and thus makes the region more unstable.