Remotely controlled self-powering electrical stimulators for osteogenic differentiation using bone inspired bioactive piezoelectric whitlockite nanoparticles

Polyaniline Protrusions on MoS2 Nanosheets for PVDF Scaffolds with Improved Electrical Stimulation

“…Figure b shows the CCK-8 assay of cells on different scaffolds, with the purpose of quantitatively analyzing cell proliferation. , Ultrasound was an acoustic intensity wave, which might generate mechanical stimulation for cell proliferation . In this work, it is found that the OD value of the control group with or without ultrasound treatment exhibited no significant difference, implying the ultrasound parameter selected in this work had almost no influence on cell proliferation, which was similar to the results reported in the literature . As expected, the OD value of cells in the control group was significantly lower than that of piezoelectric scaffolds.…”

“…51 In this work, it is found that the OD value of the control group with or without ultrasound treatment exhibited no significant difference, implying the ultrasound parameter selected in this work had almost no influence on cell proliferation, which was similar to the results reported in the literature. 52 As expected, the OD value of cells in the control group was significantly lower than that of piezoelectric scaffolds. Compared with PVDF, the OD value of cells on the 1.0PANI-MoS 2 /PVDF scaffold significantly increased, indicating that improved electrical stimulation was beneficial for cell growth.…”

Wireless electrical stimulation at the nanoscale interface induces tumor vascular normalization

“…To achieve wireless electrical stimulation based on BTO nanoparticles, we chose to use LIPUS as an external mechanical source. Due to its non-invasiveness and high tissue-penetrating capability, LIPUS can safely and efficiently manipulate the electrical signal output of piezoelectric nanoparticles in remote modality [ 30 , 31 ]. To compare the mechano-electrical responsivity of U-BTO and P-BTO nanoparticles directly, we tested the electrical signal output under LIPUS loading with different power (1 MHz, 0.25–2.25 W/cm 2 ) using a digital source meter.…”

Biodegradable magnesium phosphates in biomedical applications

“…16 As most of the Mg in the human body is stored in bone, various Mg-doped calcium phosphate (CaP) biominerals have been widely developed for biomedical applications. [17][18][19][20][21] In addition, a Mg 2+ ion has a vital influence on the crystallization of CaP biominerals, and it can regulate the phase and structure of CaPs, [22][23][24] which provides a simple strategy for the design and synthesis of bionic CaP minerals.…”