Removal of lens epithelial cells and the effect on capsulorhexis size

Abstract

Removal of anterior subcapsular LECs by aspiration helped maintain the size of the capsulorhexis opening and thus can help prevent capsule contraction syndrome.

Role of anterior capsule polishing in residual lens epithelial cell proliferation

“…21 In addition, 360-degree anterior capsule polishing is reported to prevent contraction of the capsulorhexis aperture. 5,22,23 In our study, however, contraction was not seen in either group during a 1-year follow-up. Residual LECs can cause capsule shrinkage by transforming into myofibroblasts that contract and deposit collagen.…”

Capsule contraction syndrome with haptic deformation and flexion

“…5 A small randomized controlled trial demonstrated that polishing the anterior capsule at the end of surgery reduced the risk for ACO. 9 Continuous curvilinear capsulorhexis is associated with higher rates of capsule contraction syndrome than can-opener capsulotomy. 1 Capsulorhexis size is not a reported predisposing factor, and our practice is to perform continuous curvilinear capsulorhexis of 6.0 to 8.0 mm in diameter.…”

Effect of lens epithelial cell aspiration on postoperative capsulorhexis contraction with the use of the AcrySof intraocular lens

“…Only one study has examined the effect of 360-degree capsule polishing on capsule contraction. 6 While waiting for pharmacological strategies to eliminate LECs, we investigated whether 360-degree aspiration of cells from the entire anterior capsule would minimize capsulorhexis aperture contraction.…”

“…Ursell et al 24 report improved stability of the anterior capsule-AcrySof IOL combination compared with a silicone IOL-capsule interaction. Tadros et al 6 report a 17% decrease in the capsulorhexis aperture 6 months postoperatively in eyes with a silicone optic IOL (SI-40). Our control group had only 5.6% contraction of the capsule aperture area 3 months after surgery.…”

“…4 Partial aspiration of LECs may prevent capsulorhexis aperture contraction. 5 Tadros et al 6 showed that 360-degree anterior capsule polishing reduces capsulorhexis aperture contraction in eyes with a silicone IOL (SI-40, Allergan).…”