“…Biotransformation of specific micropollutants has been observed during ammonia-oxidation in environments with high nitrifying activity (Xu et al, 2016). For example, inhibition experiments and pure culture studies showed that ammonia-oxidizing bacteria (AOB) in nitrifying activated sludge (NAS) were involved in the biotransformation of asulam, clomazone, monuron, trimethoprim, sulfonamide, and fluoroquinolone antibiotics and many other pharmaceuticals (Men et al, 2017;Wu et al, 2021;Zhou et al, 2019Zhou et al, , 2021. The complete ammonia-oxidizing (comammox) bacteria within the genus Nitrospira have only been discovered recently, but were found to occur in many different nitrifying ecosystems (Daims et al, 2015;Kits et al, 2017;Pjevac et al, 2017;van Kessel et al, 2015).…”