Renal Allograft Function and Cardiovascular Risk in Recipients of Kidney Transplantation After Successful Pregnancy

Gutiérrez, M.; González, Pedro; Delgado, I.; Gutiérrez, Eduardo; González, Esther; Siqueira, Raquel Cruzeiro de; Andrés, Amado; Morales, J. M.

doi:10.1016/j.transproceed.2009.06.042

Cited by 22 publications

(20 citation statements)

References 5 publications

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“…Graft function in the 10 -year period was similar between patients with pregnancy history and controls (12)(13)(14)(15). No significant differences are reported in the mean level of creatinine in pre-and post -pregnancy period, in many studies (12,(18)(19)(20).…”

Section: The Effect Of Pregnancy On Transplanted Kidneymentioning

confidence: 79%

“…Investigators consistently showed that pregnancy after renal transplantation generally has excellent graft survival. In 5 studies, long-term outcomes were compared between patients with kidney transplantation and a history of pregnancy and those of nulliparous as the control and no significant differences were observed in the graft function or survival (10)(11)(12)(13)(14). The reported survival rates were 61.6% to 84.8% in patients with a history of pregnancy versus 58.1% to 78.8% in the controls at the 15 -year follow-up (10, 14).…”

Section: Discussionmentioning

confidence: 99%

“…Although graft dysfunction and obstructive uropathy are reported in pregnant patients with kidney transplantation (9), studies compared the long -term outcomes of pregnancy on transplanted kidney with nulliparous transplanted controls did not show significant differences in the function or survival of graft in long term (10)(11)(12)(13)(14)(15)(16)(17) (Table 1). Graft function in the 10 -year period was similar between patients with pregnancy history and controls (12)(13)(14)(15).…”

Section: The Effect Of Pregnancy On Transplanted Kidneymentioning

confidence: 98%

“…The increased miscarriage rate after kidney transplantation is 14.0% and the rate of some adverse outcomes such as preeclampsia, preterm delivery, and delivery by cesarean section is more than that of normal population in such patients (4,13,24,25).…”

Section: Fetal and Maternal Outcomesmentioning

confidence: 99%

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Currently Available Urine-Based Tumour Markers in the Detection of New and Recurrent Urothelial Bladder Cancer

Horstmann¹

2011

Nephro Urol Mon

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Context: The current study aimed at providing an evidence -based and up-to-date review of the literature regarding the assessment and outcomes of pregnancy in patients with renal transplant. Design: It was a review of the current literature. Conclusions: According to the current study findings, the function or survival of renal allograft was not adversely affected by getting pregnant. Therefore, ideal care for these patients needs a multidisciplinary approach including maternal-fetal medicine, nephrology, and neonatology specialists.

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Section: The Effect Of Pregnancy On Transplanted Kidneymentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Section: The Effect Of Pregnancy On Transplanted Kidneymentioning

confidence: 98%

Section: Fetal and Maternal Outcomesmentioning

confidence: 99%

See 2 more Smart Citations

Currently Available Urine-Based Tumour Markers in the Detection of New and Recurrent Urothelial Bladder Cancer

Horstmann¹

2011

Nephro Urol Mon

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“…Under these conditions, patients have no increased graft loss or increased cardiovascular disease after 10 years of follow-up (62,63). Recent KDIGO guidelines recommend patients wait until their renal function is "stable" and are Ͼ1 year after transplant (64).…”

Section: For Patients Interested In Becoming Pregnant After Transplanmentioning

confidence: 99%

Topics in Transplantation Medicine for General Nephrologists

Obhrai

Leach

Gaumond

et al. 2010

Clinical Journal of the American Society of Nephrology

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Before transplantation, the general nephrologist is the primary resource for potential kidney transplantation recipients. After transplantation, the general nephrologist is increasingly managing transplant medications and complications. We provide evidence-based management strategies for common clinical issues. Linking our approach with the data allows the clinician to explore each subject in greater depth to tailor care to individual patients.

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Pregnancy in renal transplantation: Recipient and donor aspects in the Arab world

Kukla

Issa

Ibrahim

2012

Arab Journal of Urology

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ObjectiveThere are many kidney transplant recipients and living donors of reproductive age, and the prevalence of pregnancies in kidney transplant recipients can reach 55% in the Middle Eastern countries. Living kidney donation is predominant in this region. As the risks and outcomes of pregnancy should be a part of counselling for both recipients and donors, we reviewed available reports on maternal and foetal outcomes in these particular populations.MethodsInformation was obtained from retrospective analyses of a large database, and from single-centre reports indexed in PubMed on pregnancy in donors and kidney transplant recipients. The keywords used for the search included ‘fertility’, ‘kidney disease’, ‘pregnancy’, ‘maternal/foetal outcomes’, ‘kidney transplant recipient’, ‘immunosuppression side-effects’, ‘living donor’ and ‘Arab countries’.ResultsPregnancies in kidney transplant recipients are most successful in those with adequate kidney function and controlled comorbidities. Similarly to other regions, pregnant recipients in the Middle East had a higher risk of pre-eclampsia (26%) and gestational diabetes (7%) than in the general population. Caesarean section was quite common, with an incidence rate of 61%, and the incidence of pre-term birth reached 46%.ConclusionsMost living donors can have successful pregnancies and should not be routinely discouraged. Women who had pregnancies before and after donation were more likely to have adverse maternal outcomes (gestational diabetes, hypertension, proteinuria, and pre-eclampsia) in the latter, but no adverse foetal outcomes were found after donation. The evaluation before donation should include a gestational history and counselling about the potential risks.

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Renal Allograft Function and Cardiovascular Risk in Recipients of Kidney Transplantation After Successful Pregnancy

Cited by 22 publications

References 5 publications

Currently Available Urine-Based Tumour Markers in the Detection of New and Recurrent Urothelial Bladder Cancer

Currently Available Urine-Based Tumour Markers in the Detection of New and Recurrent Urothelial Bladder Cancer

Topics in Transplantation Medicine for General Nephrologists

Pregnancy in renal transplantation: Recipient and donor aspects in the Arab world

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