Renal artery thrombosis in COVID-19

Acharya, Sudeep; Anwar, Shamsuddin; Siddiqui, Fasih Sami; Shabih, Sohaib; Manchandani, Umesh; Dalezman, Solomon

doi:10.1016/j.idcr.2020.e00968

Cited by 13 publications

(10 citation statements)

References 10 publications

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“…Ischemic events have a low incidence of around 0.1-1.4%, while splenic thrombosis has not been frequently described [100]. The data suggest that COVID-19 infections can cause macro and micro thromboembolic renal dysfunction and trigger a microvascular obstruction and infarction [101,102]. Idilman et.…”

Section: Complications Of Gastrointestinal Hepatic and Renal Systemmentioning

confidence: 99%

Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms

Andrade

Siqueira

Soares

et al. 2021

Viruses

355

250

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The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-term care of COVID-19 survivors. It is thus imperative to study post-COVID (i.e., short-term) and long-COVID (i.e., long-term) effects, specifically as local and systemic pathophysiological outcomes of other coronavirus-related diseases (such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS)) were well-cataloged. We conducted a comprehensive review of adverse post-COVID health outcomes and potential long-COVID effects. We observed that such adverse outcomes were not localized. Rather, they affected different human systems, including: (i) immune system (e.g., Guillain–Barré syndrome, rheumatoid arthritis, pediatric inflammatory multisystem syndromes such as Kawasaki disease), (ii) hematological system (vascular hemostasis, blood coagulation), (iii) pulmonary system (respiratory failure, pulmonary thromboembolism, pulmonary embolism, pneumonia, pulmonary vascular damage, pulmonary fibrosis), (iv) cardiovascular system (myocardial hypertrophy, coronary artery atherosclerosis, focal myocardial fibrosis, acute myocardial infarction, cardiac hypertrophy), (v) gastrointestinal, hepatic, and renal systems (diarrhea, nausea/vomiting, abdominal pain, anorexia, acid reflux, gastrointestinal hemorrhage, lack of appetite/constipation), (vi) skeletomuscular system (immune-mediated skin diseases, psoriasis, lupus), (vii) nervous system (loss of taste/smell/hearing, headaches, spasms, convulsions, confusion, visual impairment, nerve pain, dizziness, impaired consciousness, nausea/vomiting, hemiplegia, ataxia, stroke, cerebral hemorrhage), (viii) mental health (stress, depression and anxiety). We additionally hypothesized mechanisms of action by investigating possible molecular mechanisms associated with these disease outcomes/symptoms. Overall, the COVID-19 pathology is still characterized by cytokine storm that results to endothelial inflammation, microvascular thrombosis, and multiple organ failures.

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Section: Complications Of Gastrointestinal Hepatic and Renal Systemmentioning

confidence: 99%

Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms

Andrade

Siqueira

Soares

et al. 2021

Viruses

355

250

View full text Add to dashboard Cite

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“…68 A few recent studies have also reported acute limb ischemia, renal artery thrombosis, retinitis, and optic neuritis in COVID-19 subjects and its survivors. [69][70][71] The reported neuromuscular complications like peripheral nerve injuries are predominantly idiopathic, though these can be secondary to the underlying systemic disease/ immune dysregulation, direct neural-invasion, or sometimes even related to the hospital-care (like prone positioning to treat ARDS). 72 MRI and high-resolution sonographic evaluation of the affected peripheral nerve is suggested, guiding the appropriate treatment and rehabilitative therapy in such individuals.…”

Section: Miscellaneous Manifestationsmentioning

confidence: 99%

The Conundrum of ‘Long-COVID-19ʹ: A Narrative Review

Garg¹,

Maralakunte²,

Garg³

et al. 2021

IJGM

163

117

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COVID-19 is an ongoing pandemic with many challenges that are now extending to its intriguing long-term sequel. ‘Long-COVID-19ʹ is a term given to the lingering or protracted illness that patients of COVID-19 continue to experience even in their post-recovery phase. It is also being called ‘post-acute COVID-19ʹ, ‘ongoing symptomatic COVID-19ʹ, ‘chronic COVID-19ʹ, ‘post COVID-19 syndrome’, and ‘long-haul COVID-19ʹ. Fatigue, dyspnea, cough, headache, brain fog, anosmia, and dysgeusia are common symptoms seen in Long-COVID-19, but more varied and debilitating injuries involving pulmonary, cardiovascular, cutaneous, musculoskeletal and neuropsychiatric systems are also being reported. With the data on Long-COVID-19 still emerging, the present review aims to highlight its epidemiology, protean clinical manifestations, risk predictors, and management strategies. With the re-emergence of new waves of SARS-CoV-2 infection, Long-COVID-19 is expected to produce another public health crisis on the heels of current pandemic. Thus, it becomes imperative to emphasize this condition and disseminate its awareness to medical professionals, patients, the public, and policymakers alike to prepare and augment health care facilities for continued surveillance of these patients. Further research comprising cataloging of symptoms, longer-ranging observational studies, and clinical trials are necessary to evaluate long-term consequences of COVID-19, and it warrants setting-up of dedicated, post-COVID care, multi-disciplinary clinics, and rehabilitation centers.

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“…88 Renal artery thrombosis and renal vein thrombosis have both been documented, including cases with associated renal infarction; however, these are likely rare events. [88][89][90][91][92]…”

Section: Micro or Macrovascular Injury/endothelial Activation Contributing To Ckd Riskmentioning

confidence: 99%