Renal blood‐flow changes during renal nerve stimulation in rats treated with alpha‐adrenergic and dopaminergic blockers.

Chapman, B.J.; Horn, N M; Robertson, Mark

doi:10.1113/jphysiol.1982.sp014136

Cited by 35 publications

(18 citation statements)

References 18 publications

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“…17 There is abundant morphological, biochemical, and immunohistochemical evidence for the existence of dopaminergic sympathetic neurons in the renal nerve supply of the dog. 8 -9 Some functional data also suggest the involvement of dopaminergic nerves in regulation of renal function in the rat 10 ' "; however, the amounts of DA found in the present study were compatible with its presence entirely in noradrenergic neurons. While these data do not preclude the additional existence of dopaminergic renal nerves, they do indicate that any population is likely to be small relative to that in the dog kidney.…”

Section: Figure 2 Comparison Of Neuronal Dopamine (Da) and Norepincontrasting

confidence: 51%

Catecholamines in kidneys of normotensive and genetically hypertensive rats. Effects of salt load.

Petrovic¹,

Bell²

1986

Hypertension

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The tissue content of norepinephrine, dopamine, and epinephrine was determined in different zones of the kidney in normotensive Sprague-Dawley and Otago Wistar rats and in genetically hypertensive Otago Wistar rats. One kidney in each animal was chronically denervated to allow estimation of the neuronal contribution to renal catecholamine content. In all strains, the renal cortex contained negligible amounts of nonneuronal norepinephrine and dopamine, while outer and inner medullary layers contained progressively larger amounts. Nonneuronal epinephrine was distributed fairly evenly through cortex and medulla. Neuronal norepinephrine content was similar in inner and outer cortex, substantially less in outer medulla, and not discernible in inner medulla. The amounts of neuronal dopamine were consistent with its localization predominantly in noradrenergic nerves. The renal cortices of normotensive Wistar rats contained more neuronal norepinephrine and less neuronal dopamine than those of Sprague-Dawley rats, and the cortices of hypertensive Wistar rats contained slightly more norepinephrine than those of normotensive Wistar rats. In both normotensive strains, long-term salt loading decreased selectively the neuronal norepinephrine in renal cortex. By contrast, in hypertensive animals, cortical norepinephrine was not reduced by salt loading. These results indicate that the genetically hypertensive rat may have an abnormal sympathetic reflex response to increased blood volume.

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Section: Figure 2 Comparison Of Neuronal Dopamine (Da) and Norepincontrasting

confidence: 51%

Catecholamines in kidneys of normotensive and genetically hypertensive rats. Effects of salt load.

Petrovic¹,

Bell²

1986

Hypertension

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“…Pharmacological evidence indicated that renal vessels possess both a-and P-adrenoceptors as well as dopamine receptors (Rosendorff,Bomzon,Farr & 672 Y. MAKITA modify the vasodilator response (DiSalvo & Fell, 1971;Gomer & Zimmerman, 1972). The existence of dopaminergic vasodilator nerves has also been reported (Chapman, Horn & Robertson, 1982).…”

Section: Introductionmentioning

confidence: 95%

Effects of adrenoceptor agonists and antagonists on smooth muscle cells and neuromuscular transmission in the guinea‐pig renal artery and vein

Makita

1983

British J Pharmacology

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“…The stimulus nature may be different in each type, but the underlying pathophysiology is based on proposed neurovascular reflexes that change renal blood flow including reflex renal vasospasm with intra-renal blood shunt [2-7, 12-14]. …”

Section: Discussionmentioning

confidence: 99%

Experience of a Tertiary-Level Urology Center in the Clinical Urological Events of Rare and Very Rare Incidence. III. Psychourological Events: 1. Psychic Anuria

et al. 2018

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Introduction: Psychic anuria is an old term, referring to a very rare psycho-urological event that has scarcely been studied so far. Materials and Methods: A retrospective study of the patients with psychic anuria presented to Assiut Urology and Nephrology Hospital during the period July 1991–June 2016 was done. Psychic anuria was defined, and the demographic and clinical characteristics including the methods of diagnosis and management were studied. Results: Of more than 3,800 cases of anuria, 9 female patients (0.24%) experienced psychic anuria in the age range of 17–43 years. Cardinal clinical findings included anuria for 36–72 h with absence of organic causes and normal renal function tests. Psychosocial risk factors were reported in the 9 cases. Anuria was documented by reliable history (56%) or observable urine collection (44%). Diagnosis was done by exclusion, where the investigations revealed no organic causes. Seven cases responded to the placebo intervention and 2 cases were self-limiting and resolved spontaneously. Conclusions: Psychic anuria is an extremely rare urological emergency that presents, mainly, in young adult females with unknown mechanisms. Renal vasoconstriction following psychosocial stressors is suggested. It is diagnosed by exclusion and resolves spontaneously or responds to placebo intervention as a mental distraction technique.

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Renal blood‐flow changes during renal nerve stimulation in rats treated with alpha‐adrenergic and dopaminergic blockers.

Cited by 35 publications

References 18 publications

Catecholamines in kidneys of normotensive and genetically hypertensive rats. Effects of salt load.

Catecholamines in kidneys of normotensive and genetically hypertensive rats. Effects of salt load.

Effects of adrenoceptor agonists and antagonists on smooth muscle cells and neuromuscular transmission in the guinea‐pig renal artery and vein

Experience of a Tertiary-Level Urology Center in the Clinical Urological Events of Rare and Very Rare Incidence. III. Psychourological Events: 1. Psychic Anuria

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