Renal Carcinoma with Solitary Distant Metastasis

Hubmer, G.; Gnad, H. D.; Vilits, P

doi:10.1159/000280943

Cited by 7 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The survival of the patients reported by us is considerably better than the results of nephrectomy and removal of solitary metastasis in pa tients with hypernephroma. No such patient survived 4 years [9,10]. Actually, our patient survival at 5 years is the same as reported by many authors for radical nephrec tomy of only one kidney [7],…”

Section: Discussionsupporting

confidence: 84%

Long-Term Results of Dialysis and Transplantation in Patients with End-Stage Renal Failure from Hypernephroma

Mandel¹,

Kjellstrand²

1986

Nephron

View full text Add to dashboard Cite

We analyzed long-term, 2- to 9-year results and risk factors in 13 patients treated with dialysis and transplantation for hypernephroma. Eight were dialyzed only, 6 died, 4 of them from metastatic disease that occurred in less than 8 months in 3. Five patients were also transplanted. Three died, 1 of metastatic disease. Two are alive, 1 with metastatic disease, 6 years after transplant, 3 years after diagnosis of metastasis. There were no differences in age and sex in those with early metastatic disease when compared to those without, but stage III-IV disease and time of less than 5 years between first and second nephrectomy were more common in those with early metastatic disease. These data indicate that a 7-month waiting time on dialysis is enough to avoid transplanting those with early recurrence, and that patients with stage III-IV and early reappearance of tumor in the second kidney are best treated with conservative management rather than a second total nephrectomy.

show abstract

Section: Discussionsupporting

confidence: 84%

Long-Term Results of Dialysis and Transplantation in Patients with End-Stage Renal Failure from Hypernephroma

Mandel¹,

Kjellstrand²

1986

Nephron

View full text Add to dashboard Cite

show abstract

“…This difference is more pronounced if the interval between nephrectomy and the appearance of metastases exceeds 2 years [8]. With late metastases, the 5-years survival rate of 45% is similar to that of patients with non-metastatic carcinoma [9]. In the present case, the metastatic disease was noted 2 months after nephrectomy, and the patient was apparently well 2 months later.…”

Section: Discussionsupporting

confidence: 64%

Isolated Testicular Metastases from Renal Cell Carcinoma

Indudhara¹,

Sharma²,

Rajwanshi

et al. 1990

Urol Int

View full text Add to dashboard Cite

Testicular metastasis from renal cell carcinoma is very rare. Herein we report a case of left-side renal cell carcinoma initially diagnosed to be clinically stage II, which developed left-side testicular metastases 2 months following radical nephrectomy. High inguinal orchiectomy was carried out. The patient was asymptomatic 2 months later. Although renal vein involvement in renal cell carcinoma is common and its extension into inferior vena cava well documented, tumour invasion of spermatic veins is rare.

show abstract

“…Renal adenocarcinoma is usually metastasizes in the early phase of follow‐up. The lung, bone, lymph node and liver are major sites of metastatic spread 10 . Malignant involvement of the ipsilateral adrenal gland is noted only in 1.2–10% 2–5 .…”

Section: Discussionmentioning

confidence: 99%

“…The lung, bone, lymph node and liver are major sites of metastatic spread. 10 Malignant involvement of the ipsilateral adrenal gland is noted only in 1.2-10%. [2][3][4][5] Moreover, contralateral adrenal involvement by RCC is extremely rare.…”

Section: Discussionmentioning

confidence: 99%

Adrenal metastasis from renal cell carcinoma: Significance of adrenalectomy

et al. 2002

View full text Add to dashboard Cite

Background: The present study examined adrenal metastasis resulting from renal cell carcinoma (RCC), with the aim of assessing the need for routine ipsilateral adrenalectomy during radical nephrectomy. Methods: Ipsilateral and contralateral adrenal metastases were investigated in 256 patients with RCC who had undergone radical nephrectomy from 1977 to 1996 at the Tohoku University School of Medicine.Results: Twelve of the 256 patients (4.7%) had adrenal metastasis. Ten of these 12 patients had progressed to disseminated disease with very poor prognosis. Two patients who had solitary adrenal metastases remained disease-free for 21 and 7 years. Four patients showed metastases to the contralateral adrenal gland. Adrenal metastases in seven of 12 patients were identified by preor postoperative computed tomography (CT), and in another five macroscopically during surgery. Conclusions: Adrenalectomy was regarded as a possible curative treatment for patients with solitary adrenal metastasis. However, the incidence of this kind of metastasis was minimal and contralateral adrenal metastases may occur in RCC cases. We therefore believe that adrenalectomy should only be performed if radiographic evidence reveals metastases in the adrenal gland or if gross disease is present at the time of nephrectomy.

show abstract

Renal Carcinoma with Solitary Distant Metastasis

Cited by 7 publications

References 5 publications

Long-Term Results of Dialysis and Transplantation in Patients with End-Stage Renal Failure from Hypernephroma

Long-Term Results of Dialysis and Transplantation in Patients with End-Stage Renal Failure from Hypernephroma

Isolated Testicular Metastases from Renal Cell Carcinoma

Adrenal metastasis from renal cell carcinoma: Significance of adrenalectomy

Contact Info

Product

Resources

About