Renal cell carcinoma metastatic to gallbladder: a survival advantage to simultaneous nephrectomy and cholecystectomy

Abstract

Renal cell carcinoma is a relatively uncommon cancer. Patients presenting with a renal adenocarcinoma are often found to have evidence of metastatic disease at the time of diagnosis. Herein, we describe the case of a 39-year-old male with renal cell carcinoma and a synchronous metastatic focus to the gallbladder. The patient underwent a successful simultaneous nephrectomy and cholecystectomy and is doing well 30 months after surgery without evidence of disease recurrence. A thorough metastatic work-up along with aggressive surgical intervention in patients with renal cell carcinoma and unusual metastatic foci can provide a long-term favorable outcome.

Polypoid Gallbladder Lesion in the Context of Renal Cell Carcinoma

“…Laparoscopic cholecystectomy has evolved into a standard procedure in the management of benign disease. Cholecystectomy in RCC gallbladder metastases has been reported, 5 , 6 but remains rare. The role and potential lack of adverse effects of laparoscopic management in the context of malignant disease has not been determined yet.…”

Simultaneous abdominal and retroperitoneal surgery

“…Противопоказаниями к расширению объема оперативного вмешательства являются распространенный перитонит, тяжелая кровопотеря, анестезиологический риск IV степени по ASA [3,26]. Симультанные операции в условиях экстренной хирургии оправданы только в случае, если у больного выявляют два или более острых заболевания, каждое из которых может привести к смерти [7,13,16,19,21,23].…”

Gallbladder’s Clear Cell Renal Cell Carcinoma Metastasis: A Systematic Review of the Literature

“…Resection of a solitary metastasis was associated with a 5-year survival rate of 34% in 59 cases, which is exactly the same rate as following nephrectomy in the absence of apparent metastases [28] . When metastases are synchronous, the odds of survival worsen, and most patients die within 1 year [31] . Won JY et al, in their case series of metastatic disease to the gallbladder, found that the only factor associated with prolonged survival was a R0 resection and presentation with acute cholecystitis was associated with poor survival [38] .…”