Renal cell carcinoma with cutaneous metastases

Lim, Cathy; Chan, Renee C.F.; Regan, W. M.

doi:10.1111/j.1440-0960.2005.00169.x

Cited by 23 publications

(13 citation statements)

References 12 publications

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“…The interval between the initial diagnosis of a primary tumour and associated cutaneous metastases averages 3 years; but metastases having arisen as late as 22 years after its primary tumour have been described. Late appearance does not distinguish any speciWc neoplasia, as case reports exist for colon carcinoma, larynx, renal cell, urinary bladder, and mamma carcinoma (Dorairajan et al 1999;Gowardhan et al 2004;Lim et al 2005;Braverman 2002). The probability of survival after the diagnosis of skin metastases drops below 1 year and deteriorates with multiple cutaneous metastases (Schoenlaub et al 2001;Braverman 2002).…”

Section: Disease Coursementioning

confidence: 90%

Cutaneous metastases of visceral tumours: a review

Nashan

Müller

Braun‐Falco

et al. 2008

J Cancer Res Clin Oncol

116

136

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Section: Disease Coursementioning

confidence: 90%

Cutaneous metastases of visceral tumours: a review

Nashan

Müller

Braun‐Falco

et al. 2008

J Cancer Res Clin Oncol

116

136

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“…Because of its appearance, skin metastasis of RCC may be confused with hemangioma, pyogenic granuloma, Kaposi's sarcoma, skin cysts and skin lymphoma. [8] In our case, metastatic skin lesions were about 1 cm in size, red-purple in color and nodular style. The skin metastasis of RCC was diagnosed with skin biopsy.…”

Section: Case Reportmentioning

confidence: 99%

“…Its view may be normal skin color, as well as, brown, black or purple due to the accumulation of hemosiderin. [8] The view of skin metastasis of RCC is often papules, plaques or nodules. [7] The lesions may be in milimetric size and also up to a few centimeters in size.…”

Section: Case Reportmentioning

confidence: 99%

Renal cell carcinoma presenting with cutaneous metastasis: case report

Urakçı¹

2013

TJ Oncol

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Renal hücreli karsinomun (RHK) cilt metastazı oldukça nadir olup %1-3.3 oranında görülmektedir. Biz burada tanıdan beş yıl sonra cilt metastazı gelişen bir RHK olgusu sunduk. Elli yedi yaşında erkek hastaya beş yıl önce RHK tanısı konularak sol nefrektomi yapılmıştı. Tanı anında metastazı olmayan hastada tanıdan bir yıl sonra metastaz gelişti. Hastaya palyatif amaçlı kemoterapi ve radyoterapi uygulandı. Hastanın takipleri esnasında yüzde, saçlı deride çok sayıda, yeni ortaya çı-kan, kırmızı morumsu tarzda nodüler cilt lezyonları saptandı. Nodüllerden yapılan biyopsi sonucu RHK cilt metastazı olarak değerlendirildi. Cilt metastazı geliştikten bir ay sonra hasta kaybedildi. Sonuç olarak, RHK'nın cilt metastazı oldukça nadirdir ve kötü prognoz göstergesidir.Anahtar sözcükler: Kutanöz metastaz; renal hücreli karsinom.Renal cell carcinoma (RCC) skin metastasis is quite rare, seen in the rate of 1-3.3%. We present here a RCC case that thrives skin metastasis after 5 years of diagnosis. A 57-year-old male patient was diagnosed as RCC 5 years ago and left nephrectomy was made. In the patient without metastasis at the diagnosis, metastasis developed 1 year after the diagnosis. The patient underwent palliative chemotherapy and radiotherapy. During follow-up of the patient, a large number of new emerging, purple red style nodular skin lesions were seen on the face and scalp. After the biopsy made from nodules, it was evaluated as skin metastasis of RCC. One month later that skin metastasis developed, the patient died. As a result, the skin metastasis of RCC is extremely rare, and indicator of poor prognosis. 163Renal cell carcinoma (RCC) constitutes approximately 3% of all malignancies in adults. [1] RCC constitutes about 90% of renal tumors and is one of the most lethal urogenital cancers. [2] In the average, 25% of RCCs are metastatic and the most common sites of metastasis are lung, lymph nodes, bone, liver, opposite kidney, adrenals and brain. [2] RCC, skin metastasis is quite rare, seen in the rate of 1-3.3%. [3] For anatomic localization and lymphohematogen spread, since it is far from kidney, RCC in the head and neck skin metastasis is quite rare. [4] We present here a RCC case that thrives skin metastasis after five years of diagnosis. CASE REPORTFive years ago, 57-year-old male patient with complaints of left flank pain and hematuria as a result of investigations was taken a diagnosis of RCC. Left nephrectomy operation was undergone. There was no metastasis at diagnosis. In the patient that was followed untreated, lung metastasis developed after 1 year and brain and bone metastasis developed after 2 years from diagnosis. Palliative

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“…[6] Our case presented as a solitary, well defined, painless, subcutaneous nodule of 2 × 1 cm size, firm, and nonulcerating.…”

Section: Discussionmentioning

confidence: 97%

Cutaneous metastasis in renal cell carcinoma

Ahmad

Zafar

Siddiqui

et al. 2008

J Cytol

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A case of renal cell carcinoma (RCC) occurring in a 65 year-old male presenting primarily as cutaneous metastasis to the chest, is being reported for its unusual presentation in the form of a skin nodule, even before the development of any urological presentation. RCC had metastasised to the liver as well. This case emphasises the importance of looking for a primary renal cancer in cutaneous metastasis cases as most of these patients have recurrent or multifocal metastatic disease.

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Renal cell carcinoma with cutaneous metastases

Cited by 23 publications

References 12 publications

Cutaneous metastases of visceral tumours: a review

Cutaneous metastases of visceral tumours: a review

Renal cell carcinoma presenting with cutaneous metastasis: case report

Cutaneous metastasis in renal cell carcinoma

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