Renal Collision Tumor in Association with Xanthogranulomatous Pyelonephritis

Abstract

Collision tumor is a rare condition in which two neoplasms (usually benign and malignant), both growing in the same general area, collide with each other and become intermingled. We present histopathology and imaging correlation of xanthogranulomatous pyelonephritis coexistent with squamous cell carcinoma and osteogenic sarcoma of the kidney.

An Interesting Finding of Xanthogranulomatous Pyelonephritis Revealed Concomitant Incidental Squamous Cell Carcinoma (SCC) of the Renal Pelvis

“…Studies have reported cases where squamous cell carcinoma of the kidney parenchyma mimicked XGP on radiological examination [ 16 ]. Histopathological evaluations have shown cases of XGP coexisting with squamous cell carcinoma and osteogenic sarcoma of the kidney [ 17 ]. XGP is characterized by the presence of lipid-laden, foamy macrophages and inflammatory cells in the renal parenchyma [ 18 ].…”

Renal Squamous Cell Carcinoma Presented With Bone Metastasis and Coexistence With Xanthogranulomatous Pyelonephritis: A Case Report

“…Primary renal squamous cell carcinoma is a rare cancer with a variable incidence of approximately 0.5%-15% of all urothelial cancers. 1 , 2 , 3 , 4 There are only isolated case reports and scant case series of such cases in the English literature. SCC of the renal pelvis is the second most common malignancy after adenocarcinoma.…”

Pyelonephritis: A Surgical Pathology?

“…Radiological diagnosis is usually made by the presence of an enlarged non-functioning kidney with staghorn calculus, caliceal dilatation and low attenuation areas which replace the renal parenchyma. This is secondary to inflammatory infiltrate and perinephric stranding [4].…”