Renal Complications Following Hematopoietic Stem Cell Transplantation

Abstract

Renal complications following hematopoietic stem cell transplantation (HSCT) pose substantial clinical challenges and impact patient outcomes. This chapter provides an in-depth analysis of the renal complications that may arise post-HSCT, including acute kidney injury (AKI), nephrotic syndrome, chronic kidney disease (CKD), and electrolyte imbalances. These complications occur from various factors such as nephrotoxic medications, graft-versus-host-disease (GVHD), infections, and pre-existing renal conditions. Early identification and management of renal dysfunction are crucial for optimizing patient care and prognosis. The chapter underscores the importance of vigilant monitoring, supportive measures, and timely interventions to mitigate renal complications post-HSCT. Enhanced understanding of these complications empowers clinicians to implement targeted preventive strategies and personalized therapeutic interventions, ultimately enhancing the overall outcomes and quality of life for HSCT recipients.