Renal Complications in Normal Pregnancy

Karumanchi, S. Ananth; August, Phyllis; Podymow, Tiina

doi:10.1016/b978-0-323-05876-6.00042-3

Cited by 7 publications

(9 citation statements)

References 51 publications

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“…The urine sediment is usually benign. The histologic lesion associated with preeclampsia is glomerular endotheliosis, characterized by swelling and vacuolization of endothelial cells, capillary lumen occlusion, with no prominent podocyte alterations or thrombi in the capillaries and enlarged glomeruli (45). Immunofluorescence may reveal fibrin deposits.…”

Section: Clinical Featuresmentioning

confidence: 99%

Acute kidney injury in pregnancy: a clinical challenge

Machado¹,

Figueiredo²,

Borges³

et al. 2011

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The incidence of acute kidney injury in pregnancy declined significantly over the second half of the 20th century; however, it is still associated with major maternal and perinatal morbidity and mortality. A set of systemic and renal physiological adaptive mechanisms occur during a normal gestation that will constrain several changes in laboratory parameters of renal function, electrolytes, fluid and acid-base balances. The diagnosis of acute kidney injury in pregnancy is based on the serum creatinine increase. The usual formulas for estimating glomerular filtration rate are not validated in this population. During the first trimester of gestation, acute kidney injury develops most often due to hyperemesis gravidarum or septic abortion. In the third trimester, the differential diagnosis is more challenging for the obstetrician and the nephrologist and comprises some pathologies that are reviewed in this article: preeclampsia/HELLP syndrome, acute fatty liver of pregnancy and thrombotic microangiopathies.

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Section: Clinical Featuresmentioning

confidence: 99%

Acute kidney injury in pregnancy: a clinical challenge

Machado¹,

Figueiredo²,

Borges³

et al. 2011

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“…These females need serial monitoring. [5] Preconceptional hypertension leads to IUGR, pre-eclampsia, preterm labor, and accelerated decline in renal functions. Perinatal mortality is 23% versus 4% in normotensives with CKD.…”

Section: Effects Of the Renal Insufficiency On Pregnancymentioning

confidence: 99%

“…Complications, including SGA preterm labor and stillbirth, are increased even in mild renal insufficiency. [5,21,22] Pregnancy in patients on dialysis-Pregnancy occurs only in 1% of patients. The cause of infertility is multifactorial.…”

Section: Effect Of Pregnancy On Renal Diseasementioning

confidence: 99%

“…The effect of pregnancy on FSGS, IgA, and Reflux nephopathy is controversial. [5] DN has accelerated progression in 45% of patients. [5,20] Lupus nephritis-50% experience a flare during pregnancy although it is less common in patients who have been in remission for > 6 months.…”

Section: Effect Of Pregnancy On Renal Diseasementioning

confidence: 99%

“…[5,6] urinary Tract Infections Urinary tract infections (UTIs) are the most common renal disease occurring during pregnancy and range from asymptomatic bacteriuria to pyelonephritis. UTIs have been associated with small for gestational age (SGA) babies, premature labor, intrauterine fetal death (IUD), anemia, and hypertension in mother.…”

Section: Renal Diseases Occurring In Pregnancymentioning

confidence: 99%

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Kidney and pregnancy

Sahay¹

2012

J Acad Med Sci

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Pregnancy is associated with many physiological changes in the renal system. Pregnancy can alter the course of some renal diseases as also pre-existing renal diseases may affect pregnancy outcomes. Pregnancy may be complicated by hypertension which warrants proper management. Acute kidney injury may complicate pregnancy. With chronic kidney diseases on the rise, it is important for the physician to be aware of management of pregnancy in these patients. Kidney transplant recipients have their unique set of problems and management of these patients poses a challenge for the physician. Hence, this review highlights the management of pregnant patients with renal diseases including issues related to dialysis and transplantation.

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Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy

Crane

Delaney

2008

Journal of Obstetrics and Gynaecology Canada

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Renal Complications in Normal Pregnancy

Cited by 7 publications

References 51 publications

Acute kidney injury in pregnancy: a clinical challenge

Acute kidney injury in pregnancy: a clinical challenge

Kidney and pregnancy

Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy

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