Renal excretion of electrolytes during tmpah

Ghiotto, G; Cora, D; Debiasi, S; Maggia, A

doi:10.1016/0009-8981(59)90016-6

Cited by 2 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, unlike in our study, no precautions to prevent volume expansion were included in the studies by G hiotto et al [8], Selkurt and Shade [10] recently noted natriuresis and kaliuresis in monkeys given PAH.…”

Section: Discussionmentioning

confidence: 82%

“…Seven of the eight patients reported by G hiotto el al. [8] were hypertensive patients and it has been shown by Buckalew etal. [9] that the exaggerated natriuresis of hypertension is probably due to an abnormal sodium reabsorption in the loop of Henle.…”

Section: Discussionmentioning

confidence: 99%

“…Previously, G hiotto el al. [8] measured renal electrolyte excretion during Tm-PAH and found, as we did, that both sodium and potassium clearance increased. However, these authors also measured a significant, twofold in crease in chloride clearance whereas our results demonstrate no change ( fig.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

The Natriuretic Effect of <i>p</i>-Aminohippurate in Man

Bennett

Roberts

Porter

1976

Nephron

View full text Add to dashboard Cite

The effects of p-aminohippurate (PAH) on electrolyte clearances were measured in 8 human volunteers. At plasma PAH levels used to measure renal plasma flow, the only significant increase was in sodium clearance, while with PAH levels used to measure maximum tubular secretion, the clearances of sodium, potassium and phosphorus were all significantly increased. The natriuresis combined with a depression of free water clearance and the absence of a chloruresis led to the conclusion that PAH- changed the anion composition of the filtrate delivered to the ascending limb, thus interfering with coupled Na⁺ reabsorption. This finding must be taken into account when electrolyte excretion is being measured during PAH infusion. A similar mechanism may operate in patients with chronic uremia whose endogenous hippurate level is increased.

show abstract

Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Natriuretic Effect of <i>p</i>-Aminohippurate in Man

Bennett

Roberts

Porter

1976

Nephron

View full text Add to dashboard Cite

show abstract

The distribution of intracellular alkali metals in Reference Man

Williams¹,

Leggett²

1987

Phys. Med. Biol.

View full text Add to dashboard Cite

A review of recent literature and a re-analysis of data used in Publication 23 of the International Commission on Radiological Protection (ICRP) have revealed several problems regarding the distribution of the predominantly intracellular alkali metals potassium, rubidium and caesium in ICRP Reference Man. In this paper we re-evaluate the distribution of the intracellular alkali metals in humans and we offer an approach for selecting reference concentrations for the organs of a typical adult human. For non-skeletal tissues, reference values for K, Rb and Cs are determined as a trimmed weighted mean of reported values remaining after studies involving apparently questionable populations or measurement techniques have been eliminated. The skeleton is treated as a special case, with explicit consideration being given to the heterogeneous distribution of these elements among different regions and different types of skeletal tissue. The most significant suggested changes for the intracellular alkali metals are for Rb in the skeleton and total body. ICRP Reference Man has a total Rb content of 0.68 g, compared with our estimate of only 0.25 g, and a skeletal Rb content of 0.21 g, compared with our estimate of only 0.013 g. This has important dosimetric implications for radiorubidium, because the retention model for Rb given in ICRP Publication 30 assigns a large portion of an intake to the skeleton on the basis of the large skeletal Rb content assigned to Reference Man in ICRP Publication 23.

show abstract

Renal excretion of electrolytes during tmpah

Cited by 2 publications

References 9 publications

The Natriuretic Effect of <i>p</i>-Aminohippurate in Man

The Natriuretic Effect of <i>p</i>-Aminohippurate in Man

The distribution of intracellular alkali metals in Reference Man

Contact Info

Product

Resources

About