Renal function in respiratory distress syndrome

Guignard, Jean‐Pierre; Torrado, A.; Mazouni, S.M.; Gautier, E

doi:10.1016/s0022-3476(76)81129-8

Cited by 148 publications

(65 citation statements)

References 23 publications

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“…However, other studies values of the patients in group A (not exposed to indometh-showed a marked decrease in GFR in infants with RDS acin or betamethasone). No significant difference was pre- (15,16). Our patients were hemodynamically stable (disent between the GA-adjusted GFR values of the patients uresis > 1 mL/kg/h; systolic and diastolic blood pressure in group D (prenatal exposure to both betamethasone and above the third percentile adjusted for GA) and had no indomethacin) and group A (not exposed to indomethacin hypoxemia or hypercapnia.…”

Section: Resultsmentioning

confidence: 65%

Effects of Prenatal Exposure to Betamethasone and Indomethacin on the Glomerular Filtration Rate in the Preterm Infant

et al. 1994

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Section: Resultsmentioning

confidence: 65%

Effects of Prenatal Exposure to Betamethasone and Indomethacin on the Glomerular Filtration Rate in the Preterm Infant

et al. 1994

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“…The arterial pC02 influences the response to hypoxia in that hypocapnia is associated with diuresis and hypercapnea results in a decreased renal blood flow. Additionally, Guignard et al (9) has shown that p 0 2 was the same in newborns with moderate or severe impairment of renal function, suggesting factors other than arterial oxygen tension may be important. Using the piglet, Reddy et al (14) observed an increase in renal blood flow secondary to moderate degrees of hypercapnea and acidosis and a decrease in renal blood flow with severe hypercapnea and acidosis.…”

Section: Discussionmentioning

confidence: 98%

“…Recent observations have indicated nation of i n~l i n and sodium and potassium concentration. Artethat newborn infants with respiratory distress become oliguric rial blood samples for determination of inulin, sodium and (4, l g ) , have defects in renal acidification (1,19), and have potassium, hematocrit, and plasma renin activity were obtained diminished inulin and p-aminohippurate clearances (9). How-midway through each 20-min clearnace period.…”

mentioning

confidence: 99%

Effects of Asphyxia on Renal Function in the Newborn Piglet

et al. 1978

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Summarveter was advanced into the abdominal aorta from the right femoral artery. This catheter was used for the determinatioiof This investigation was undertaken to determine the nature of blood pressure and heart rate and for sampling arterial blood. acute alterations in renal function following the production of Radioactive injections were made through a third h~~o x e m i a , h~~e r c a r b i a , and acidosis in newborn piglets 6-96 catheter (PE-90) placed in the ascending aorta by way of the left hr of age* After com~letion of the procedure piglets carotid artery. The urinary bladder was isolated through a small were allowed to recover from the effects of anesthesia. When midline abdominal incision and catheterizedThe posidead space was increased arterial Oxygen tion of all catheters was confirmed by inspection at the end of decreased whereas arterial carbon dioxide tension and hydrogen the experiment. ion concentration increased. There was little change in glomerAfter suturing the skin incisions all wounds were infiltrated ular fdtration rate. Total renal blood flow decreased and renal with lidocaine. Anesthesia was discontinued and the piglets were increased * 78 mm Hg/ placed upright in a supporting sling and allowed to recover from liter/mm/m2 to 1422 * 504). There was no change in distribu-anesthesia for hr. During the surgical procedure and the tion of intrarenal blood flow. Sodium excretion and urinary flow experiment the piglets were maintained at a body temperature rate demonstrated significant parallel increases following the of 380 using a Merco infant Under these conditions the increase in dead space. Plasma renin concentration increased animals remained calm and undisturbed in the sling, often from 67 to 110 ng/ml.sleeping during the experiment. Rectal temperature was continuously monitored using a Yellow Springs thermister. After Speculation completion of the surgical procedure the piglets were intubated Hypoxia, hypercarbia, and acidosis produced changes in renal with a 3.5 mm Portex endotracheal tube. Baseline determinafunction in newborn piglets. Therapeutic approaches to the tions were made and then a dead space 45 cc/ newborn human with respiratory distress must consider the kg) Was added to the tube in order to produce potential for modifications of renal function which may be hypoxia and hypercarbiadetrimental to the infant.Tritiated methoxy inulin (1 pCi/ml) was infused into the femoral vein at a rate of 0.04 ml/min beginning 1 hr before the onset of the experiment. During each clearance period urine The effects of respiratory distress on cardiopulmonary func-collections were made in preweighed flasks under oil. Urine tion in the newborn infant have been extensively studied. flow rate was estimated from the change in weight without However, renal function during this disease process has not ~0"ection for Specific gravity. Urine Was collected for determibeen adequately described. Recent observations have indicated nation of i n~l i n and sodium and potassium concentration. Artethat newbo...

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“…[3][4][5][6][7][8][9] Di antara ke-empat penyebab utama morbiditas bayi yang dirawat di Subbagian Neonatologi RSCM/ FKUI Jakarta, asfiksia neonatorum menempati urutan cukup bulan dengan asfiksia berat, mendapatkan 61% mengalami GGA sedangkan pada 33 bayi dengan asfiksia sedang tidak ditemukan GGA.…”

Section: 2unclassified

“…11 Gejala gangguan fungsi ginjal pada neonatus sangat tidak khas dan sering merupakan bagian dari disfungsi multiorgan seperti pada sindrom gawat nafas neonatorum yang berat. [3][4][5][6]10 Stapleton 12 melaporkan bahwa 9 di antara 15 kasus gagal ginjal akut (GGA) pada neonatus yang dirawat di ICU mempunyai riwayat asfiksia perinatal dengan angka kematian akhir GGA berkisar antara 37-78%.…”

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Hubungan Asfiksia Neonatorum dengan Gangguan Fungsi Ginjal pada Bayi Baru Lahir

Umboh¹

2016

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Asfiksia neonatorum merupakan problem kesehatan pada bayi baru lahir yang dapat menyebabkan gagal ginjal akut jika tidak ditangani dengan baik. Tujuan: untuk mengetahui hubungan antara derajat asfiksia neonatorum dengan derajat gangguan fungsi ginjal Metoda: penelitian analitik observasional pada bayi baru lahir di bangsal Neonatologi Bagian IKA/RSUP Manado antara bulan Agustus 1997-Februari 1998 yang memenuhi kriteria dilakukan pengukuran kadar ureum dan kreatinin serum serta penentuan laju filtrasi glomerulus (LFG). Data dianalisis dengan uji Anova dan Chi-Square. Hasil: di antara 129 bayi baru lahir yang memenuhi kriteria terdiri dari 49 bayi sehat, 50 asfiksia ringan-sedang, dan 30 asfiksia berat. Terdapat perbedaan bermakna kadar serum ureum dan kreatinin serta LFG antara kelompok bayi sehat dengan asfiksia berat dan antara kelompok asfiksia ringan-sedang dengan asfiksia berat (p<0,01). Lima dari 30 kasus asfiksia berat mengalami gagal ginjal akut dan terdapat hubungan bermakna antara derajat asfiksia dengan derajat gangguan fungsi ginjal (p<0,01). Kesimpulan: terdapat perbedaan antara kadar ureum dan kreatinin serum serta LFG antara bayi asfiksia berat dengan bayi sehat dan asfiksia ringan-sedang. Terdapat pula hubungan antara derajat asfiksia dengan derajat gangguan fungsi ginjal.Kata kunci: bayi baru lahir -asfiksia -gangguan fungsi ginjal Sari

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Renal function in respiratory distress syndrome

Cited by 148 publications

References 23 publications

Effects of Prenatal Exposure to Betamethasone and Indomethacin on the Glomerular Filtration Rate in the Preterm Infant

Effects of Prenatal Exposure to Betamethasone and Indomethacin on the Glomerular Filtration Rate in the Preterm Infant

Effects of Asphyxia on Renal Function in the Newborn Piglet

Hubungan Asfiksia Neonatorum dengan Gangguan Fungsi Ginjal pada Bayi Baru Lahir

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