Renal insufficiency in children born preterm: examining the role of neonatal acute kidney injury

Pulju, Margaret; Pruitt, Cassandra; Reid-Adam, Jessica; Spear, Emily; Stroustrup, Annemarie; Green, Robert S.; Weintraub, Andrea S.

doi:10.1038/s41372-021-01097-4

J Perinatol

2021

DOI: 10.1038/s41372-021-01097-4

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Renal insufficiency in children born preterm: examining the role of neonatal acute kidney injury

Margaret Pulju

Cassandra Pruitt

Jessica Reid-Adam

et al.

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2024

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Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates

Starr,

Harer,

Steflik

et al. 2024

JAMA Netw Open

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ImportanceKidney disease is common in infants admitted to the neonatal intensive care unit (NICU). Despite the risk of chronic kidney disease (CKD) in infants discharged from the NICU, neither evidence- nor expert-based recommendations exist to guide clinical care after discharge.ObjectiveTo develop recommendations for risk stratification and kidney health monitoring among infants after discharge from the NICU.Evidence ReviewAt the National Institute of Health–supported Consensus Workshop to Address Kidney Health in Neonatal Intensive Care Unit Graduates meeting conducted in February 2024, a panel of 51 neonatal nephrology experts focused on 3 at-risk groups: (1) preterm infants, (2) critically ill infants with acute kidney injury (AKI), and (3) infants with critical cardiac disease. Using established modified Delphi processes, workgroups derived consensus recommendations.FindingsIn this modified Delphi consensus statement, the panel developed 10 consensus recommendations, identified gaps in knowledge, and prioritized areas of future research. Principal suggestions include risk stratification at time of hospital discharge, family and clinician education and counseling for subsequent kidney health follow-up, and blood pressure assessment as part of outpatient care.Conclusions and RelevancePreterm infants, critically ill infants with AKI, and infants with critical cardiac disease are at increased risk of CKD. We recommend (1) risk assessment at the time of discharge, (2) clinician and family education, and (3) kidney health assessments based on the degree of risk. Future work should focus on improved risk stratification, identification of early kidney dysfunction, and development of interventions to improve long-term kidney health.

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Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates

Starr,

Harer,

Steflik

et al. 2024

JAMA Netw Open

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Erhöht eine neonatale AKI das Risiko einer Niereninsuffizienz im Kindesalter?

2021

Neonatologie Scan

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Renal insufficiency in children born preterm: examining the role of neonatal acute kidney injury

Cited by 2 publications

References 48 publications

Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates

Kidney Health Monitoring in Neonatal Intensive Care Unit Graduates

Erhöht eine neonatale AKI das Risiko einer Niereninsuffizienz im Kindesalter?

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