Renal Pelvic Tumors

Abstract

A study was made of 35 patients with tumors of the renal pelvis. Tumors were indipendently graded and staged by a newly proposed method. The method of staging correlated well with grading of renal pelvic tumors and bore a direct relationship with prognosis. The high incidence of associated urothelial tumors, especially on the involved side, mandated radical nephroureterectomy including a bladder cuff as the treatment of choice.

Impact of the 1998 World Health Organization/International Society of Urological Pathology classification system for urothelial neoplasms of the kidney

“…However, unlike the majority of urothelial neoplasms of the bladder which are noninvasive at presentation, 37 many studies of renal pelvic tumors have shown that most patients present with invasion, with only a 3.5-34% incidence of noninvasive disease. 14,15,19,[22][23][24]38,39 In our analysis and others, 20 a significantly greater number of cases demonstrated low-stage disease than highstage disease (69% rpT1 disease vs 31% ZpT2 disease), which closely approximates the 70% of bladder tumors which are 'superficial' (pTa, pTIS, pT1) at presentation. 36,37 In two more recent series of renal pelvic tumors, Gomez et al 38 and Olgac et al 39 also reported that a slightly greater number of tumors were low stage (rpT1) than high stage.…”

“…The prognosis of patients with these tumors has repeatedly been shown to depend on the tumor stage and grade. [9][10][11][13][14][15][17][18][19][21][22][23][24] At nephrectomy, our study group was divided nearly equally into those with noninvasive disease and those with an invasive component ( Table 2). Nielsen and Ostri 21 in their study of primary tumors of the renal pelvis had a slightly greater percentage (56%) of noninvasive tumors.…”

“…5 In certain regions of the world, and in patients with certain tubulointerstitial nephritides, the incidence of urothelial neoplasms of the renal pelvis and ureter is quite high, with renal pelvic carcinoma accounting for as much as 68% of renal tumors in some series. 4,6 As a result of the general scarcity of these tumors, [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] coupled with the even lower incidence of ureteral urothelial tumors (1% of urothelial neoplasms), 2 a large proportion of published reports incorporate tumors at both sites into single studies. There have been few analyses of renal pelvic urothelial neoplasms recently in the pathology literature.…”

Lymph Node Metastasis in Patients with Carcinomas of the Renal Pelvis and Ureter

“…Pathological stage, grade, multiplicity of the tumor and synchronous or metachronous bladder carcinoma have been reported to be prognostic factors of upper tract urothelial carcinoma [11, 12, 13, 14, 15]. Our results showed that lymph node metastasis was the only independent and significant prognostic factor revealed by multivariate analysis using Cox’s proportional hazards model.…”

Renal pelvic transitional cell carcinoma. The role of the kidney in tumor–node–metastasis staging

“…The most widely used staging system for renal pelvic transitional cell carcinoma (renal pelvic cancer) is that of Grabstald et d.,' and other staging systems have subsequently been described (Table l). [2][3][4][5] In general, renal pelvic cancer staging systems have the disadvantage of being based on a bladder cancer model6 because both are urothelial malignancies. Although histologically similar, they are anatomically and biologically dissimilar.…”