Renal Replacement Lipomatosis with Psoas Abscess Mimicking as Xanthogranulomatous Pyelonephritis

Nathani, Sanjay; Singh, Kapsioor; Mehta, Pooja

doi:10.4172/2168-9857.1000204

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…RRL is most commonly seen in association with calculus disease (in >70% patients), however it can be associated with other chronic inflammatory pathologies such as chronic pyelonephritis, renal tuberculosis and transplant patients. 1,2 The mildest form of renal lipomatosis is usually seen in the sixth and seventh decade associated with obesity, atherosclerosis or use of exogenous steroids, and it has no clinical significance. 4 Danza FM et al reported their experience with 18 cases of replacement lipomatosis: 6 patients had the massive form, one of them bilateral, 5 patients had associated xanthogranulomatous pyelonephritis and 7 had an initial focal form.…”

Section: Discussionmentioning

confidence: 99%

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Renal replacement lipomatosis with granulomatous inflammation – A case report and review of literature

R¹,

Sowmya²,

Prabhu³

et al. 2022

ACHR

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Renal replacement lipomatosis can be defined as the proliferation of fibrofatty tissue which subsequently replace the renal parenchyma. It is usually benign unilateral and occurs as a result of severe atrophy or destruction of the renal parenchyma, due to a calculus with secondary proliferation of renal sinus, renal hilus, and perirenal fatty tissue to a variable extent.A 55yr old female presented to surgeon with history ofpain and swelling in right flank. On CECT abdomen there was seen non functional right kidney with staghorn calculi along with perirenal abscess. Patient was treated with nephrectomy and drainage of collection. Intraoperatively Perirenal Abscess extending to psoas and iliopsoas region along with dense adhesion between kidney and liver was found. The multiple sections studied from the lesion showed extensive fibrofatty tissue with few tubule like structures lined by cuboidal epithelium and containing dense eosinophilic secretions. There is seen mixed inflammatory infiltrates with granulomas. Histological features confirmed that Renal replacement lipomatosis with granulomatous inflammation.The clinical importance of RRL is that it stimulates fat-containing tumors in the kidney or its vicinity such as lipomas, angiomyolipomas and liposarcomas can be misdiagnosed preoperatively. Hence this case report has been presented to create awareness of this condition among the pathologist and practicing urosurgeons.

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Section: Discussionmentioning

confidence: 99%

“…It is seen with calculus disease in 70% of cases and associated with chronic inflammation and hydronephrosis. [1][2][3][4]…”

Section: Introductionmentioning

confidence: 99%

Renal replacement lipomatosis with granulomatous inflammation – A case report and review of literature

R¹,

Sowmya²,

Prabhu³

et al. 2022

ACHR

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Histomorphological Analysis of Nephrectomy Specimens

Kulkarni

Bm²,

Devi³

et al. 2022

Acta Medica International

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Introduction: For a range of kidney abnormalities, including both neoplastic and nonneoplastic disorders, nephrectomy is a popular surgical treatment. We conducted this study to examine the range of lesions found in the nephrectomy specimens obtained and to ascertain the distribution of these lesions by age and sex. Materials and Methods: This study was conducted in the department of pathology, from 2017 to 2022. All nephrectomy specimens received during 5 years were included. Results: The spectrum of renal lesions observed in the study included both neoplastic (43.75%) and nonneoplastic (56.25%) conditions. Nineteen patients were males (59.37%) and 13 were females (40.62%) (M: F = 1.4:1). The most common entity in the nonneoplastic category was chronic pyelonephritis (n = 9, 28.12%). In our study, we documented two unusual cases of renal replacement lipomatosis (RRL), a type of pseudotumor related to nonfunctioning kidneys. Fourteen patients underwent nephrectomy for neoplastic conditions such as Wilm's tumor and renal cell carcinoma (RCC). Conclusion: Nephrectomy for the nonneoplastic condition was performed more frequently in our series. Histopathological evaluation of nonneoplastic nephrectomy specimens must be thoroughly considered, particularly in unusual circumstances such as RRL, where a preoperative erroneous initial impression of a malignant lesion such as angiomyolipoma or liposarcoma is possible.

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Renal Replacement Lipomatosis with Psoas Abscess Mimicking as Xanthogranulomatous Pyelonephritis

Cited by 2 publications

References 8 publications

Renal replacement lipomatosis with granulomatous inflammation – A case report and review of literature

Renal replacement lipomatosis with granulomatous inflammation – A case report and review of literature

Histomorphological Analysis of Nephrectomy Specimens

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