Renal sarcoma – a rare parenchymal tumor with a very poor prognosis

Abstract

Le sarcome rénal-une tumeur parenchymateuse rare avec un pronostic très mauvais Le but de cet article était d'analyser les caractéristiques pronostiques, la présentation clinique, le diagnostic et le traitement des sarcomes rénaux primaires. Une revue approfondie de la littérature a été réalisée à l'aide de la base de données PubMed. Les sarcomes du rein sont des tumeurs malignes très rares, avec un très mauvais pronostic par rapport aux autres sarcomes urogénitaux. Plusieurs types histologiques ont été rapportés, le type le plus courant étant le léiomyosarcome. Outre la résection chirurgicale complète à larges marges, des facteurs anatomiques, histologiques, moléculaires

Etiologies, Gross Appearance, Histopathological Patterns, Prognosis, and Best Treatments for Subtypes of Renal Carcinoma: An Educational Review

“…There are genomic mutations that significantly impact the disease prognosis and are associated with a high metastasis potential and an independent prognostic factor for shorter survival times in patients with LMS. There are genomic mutations that significantly impact the disease prognosis and are associated with a high metastasis potential and an independent prognostic factor for shorter survival times in patients with LMS such as deletions in the 4q31 and 18q22 regions and duplication at 1q21 [ 62 ].…”

Metastatic melanoma presenting as undifferentiated tumour of unknown primary site: an immunohistochemical algorithm

“…The authors declare that all the procedures and experiments of this study respect the ethical standards in the Helsinki Declaration of 1975, as revised in 2008 (5), as well as the national law. Informed consent was obtained from all the patients included in the study"…”

“…Less than 10% of all melanoma patients present with unknown primary tumour site 2 . Taking into consideration that tumours of unknown primary site represent up to 5% of all cancers and are among the top six causes of cancer deaths [3][4][5] , an accurate diagnostic decision is crucial as treatment approaches are fundamentally distinct for different types of tumor 6 . THE OBJECTIVE OF THE STUDY was to analyse the management of undifferentiated unknown primary site tumours from the pathologist point of view and assess the essential features distinguishing malignant melanoma from other histologic mimics, with emphasis on the immunohistochemical algorithms useful in diagnosis.…”