Renal tumor infarction with absolute ethanol

Rabe, FE; Yune, Heun Y.; Richmond, B D; Klatte, Eugene C.

doi:10.2214/ajr.139.6.1139

Cited by 53 publications

(8 citation statements)

References 14 publications

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“…17,18 It was effective in producing renal ablation without causing damage to the parenchyma or vasculature of any other area in the body except the kidney. 17,18 It was effective in producing renal ablation without causing damage to the parenchyma or vasculature of any other area in the body except the kidney.…”

Section: Discussionmentioning

confidence: 99%

“…19 Absolute ethanol injection also has been used for hemostasis of bleeding esophageal varices 20 and also for the sclerotherapy for peripheral arteriovenous malformations. 18 It is easy to prepare for injection and has the ability to penetrate deeply into the vasculature. 18 It is easy to prepare for injection and has the ability to penetrate deeply into the vasculature.…”

Section: Discussionmentioning

confidence: 99%

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Selective portal vein embolization with absolute ethanol induces hepatic hypertrophy and makes more extensive hepatectomy possible

Ogasawara

Uchino

et al. 1996

Hepatology

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Portal vein embolization has been used recently to decrease the amount of the liver to be resected and to enhance the function of the remaining hypertrophied lobes. We have observed a strong contact destructivity of absolute ethanol and used it for portal vein embolization. The present study was performed to produce hepatic hypertrophy and to show histopathologic changes that follow ethanol embolization of rat liver. Hepatic proliferation and histopathology were studied in rats receiving low and high doses of absolute ethanol via portal vein and rats undergoing 70% hepatectomy alone. The liver weight of the unresected and unembolized lobes increased rapidly after embolization and hepatectomy. Although the increase was more rapid in the high-dose group than the low-dose group in early days, the final results were not different from each other and were almost equal to those after hepatectomy. Complete obstruction of portal venous branches and massive necrosis were the main histopathologic observations after portal vein embolization with all doses of ethanol. Because the mortality rate in the low-dose group was lower than in the high-dose group and extensive necrosis of the liver parenchyma and subsequent regeneration was sufficient, using minimum dose of ethanol was much safer. Based on the biochemical and hematologic parameters, portal vein embolization with low-dose ethanol did not impair liver function more than hepatectomy alone during the initial 14 days. Portal vein embolization with absolute ethanol makes more extensive hepatectomy possible by reducing the volume necessary to resect and preserves the function of the remaining liver.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Selective portal vein embolization with absolute ethanol induces hepatic hypertrophy and makes more extensive hepatectomy possible

Ogasawara

Uchino

et al. 1996

Hepatology

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“…many investigators have reported the usefulness of absolute ethanol. mechanisms of occlusion and the adverse effects of the method (I, 3, 4, 6,12, IS, 16,19). There are, however, no reports on the effects of treatment with absolute ethanol in the experimentally implanted tumor.…”

Section: Resultsmentioning

confidence: 99%

Effect of Ethanol Induced Occlusion of the Renal Artery in Rabbit Kidney Implanted with VX2 Carcinoma

Imai¹,

Kajihara²,

Nishishita³

et al. 1989

Acta Radiol

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The effects of injection of absolute ethanol into the renal artery were investigated in 13 rabbit kidneys previously implanted with VX2 carcinoma. Eight rabbits with implanted tumors served as controls. The effects were evaluated by angiography and histology. Three days after implantation, tumors were demonstrated by angiography as relatively hypovascular areas in the subcapsular cortex of the kidneys. Following angiography, absolute ethanol (0.3 ml/kg) was injected into the renal artery. Repeat angiography with barium sulphate was performed after an additional 3 days (10 ethanol treated animals, 2 controls), 10 days (2 treated, I control) or 14 days (I treated, 0 control). In treated animals the tumors were markedly smaller in comparison with those of the control group. The occlusion procedure, however, did not completely eradicate tumor cells. The histologic study of the implanted tumor confirmed the findings previously reported that viable tumor cells still remained in the peripheral portions of infarcted areas. This study demonstrated the beneficial, though not curative, short-term effects of transcatheter renal artery treatment with absolute ethanol in malignant renal tumors.

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“…and Rabe et a/. [27,28] described colon/renal infarctions and abscesses, Lohr et a/. and Lammer eta/.…”

Section: Discussionmentioning

confidence: 99%

Interventional CT and MRI combined with microendoscopy for low back pain therapy

Grönemeyer

Melzer

Seibe

1998

Minimally Invasive Therapy & Allied Technologies

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Acute and chronic back pain is the second most significant medical problem world-wide. Microinvasive CT-guided treatments of the spine are routine in our department. For this study, newlydeveloped procedures in an open 0.064 T and 0.2 T magnetic resonance imaging (MRI) scanner were compared with interventional CT. 340 patients who underwent microtherapeutic treatment took part in the study: 80 had percutaneous laser nucleotomies (PLNT), 100 had facet joint and 100 periradicular therapies (PRT); another 60 patients had ilio-sacral joint infiltrations. For PLNT a Neodymium YAG laser was used: for scar tissue treatment a Holmium YAG laser was used: for the other treatments, local anesthesia and cortisone, and 1 .O cm3 50-96% ethanol (used for denervation in treatment of chronic facet joint pain) were instilled. 100 endoscopic treatments with systems 0.29-1.8 mm in diameter were undertaken: 20 on the facet joints, 80 inside the foramen intervertebrae, before and inside the disc after laser nucleotomy. Before treatment, 340 patients had a pain score of 70-1 00 on a visual analogue scale (VAS). The average pain score before therapy was 86%, after treatment it decreased to 7% (6 month follow-up). Neurologic deficits improved in 87% of cases after endoscopic discectomy (73% at follow-up). In MRI open access allows near real-time guidance of instruments. But the last 3.5 mm at the tip of the instruments is not easy to define. lnterventional MRI is a routine technique in low risk areas, as in facet and ilio-sacral joints. CT-guidance is now the standard technique. In the future, endoscopes, drugs, lasers, RF-probes, cryosticks and mechanical instruments will be guided inside tomographic scanners for routine spinal work.

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Renal tumor infarction with absolute ethanol

Cited by 53 publications

References 14 publications

Selective portal vein embolization with absolute ethanol induces hepatic hypertrophy and makes more extensive hepatectomy possible

Selective portal vein embolization with absolute ethanol induces hepatic hypertrophy and makes more extensive hepatectomy possible

Effect of Ethanol Induced Occlusion of the Renal Artery in Rabbit Kidney Implanted with VX2 Carcinoma

Interventional CT and MRI combined with microendoscopy for low back pain therapy

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