Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies

Veisi, Parisa; Zarezade, Meysam; Rostamkhani, Helya; Ghoreishi, Zohreh

doi:10.1186/s12906-022-03768-x

Cited by 3 publications

(1 citation statement)

References 58 publications

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“…Various studies have shown that ginger can be an anti-inflammatory agent in treating type 2 diabetes mellitus [52,53]. Carvalho et al [54] found that the daily consumption of ginger in a 3-month human study reduced the level of triglycerides, fasting blood sugar, and LDL-cholesterol in patients with type 2 diabetes mellitus.…”

Section: Effect Of Mo and Ginger On Type 2 Diabetes Mellitusmentioning

confidence: 99%

Suppression of Inflamm-Aging by Moringa oleifera and Zingiber officinale Roscoe in the Prevention of Degenerative Diseases: A Review of Current Evidence

Sahardi

Makpol

2023

Molecules

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Inflammation or inflamm-aging is a chronic low-grade inflammation that contributes to numerous types of degenerative diseases among the elderly and might be impeded by introducing an anti-inflammatory agent like Moringa oleifera Lam (moringa) and Zingiber officinale Roscoe (ginger). Therefore, this paper aims to review the role of moringa and ginger in suppressing inflamm-aging to prevent degenerative diseases. Various peer-reviewed publications were searched and downloaded using the reputed search engine “Pubmed” and “Google Scholar”. These materials were reviewed and tabulated. A comparison between these previous findings was made based on the mechanism of action of moringa and ginger against degenerative diseases, focusing on their anti-inflammatory properties. Many studies have reported the efficacy of moringa and ginger in type 2 diabetes mellitus, neurodegenerative disease, cardiovascular disease, cancer, and kidney disease by reducing inflammatory cytokines activities, mainly of TNF-α and IL-6. They also enhanced the activity of antioxidant enzymes, including catalase, glutathione, and superoxide dismutase. The anti-inflammatory activities can be seen by inhibiting NF-κβ activity. Thus, the anti-inflammatory potential of moringa and ginger in various types of degenerative diseases due to inflamm-aging has been shown in many recent types of research.

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Section: Effect Of Mo and Ginger On Type 2 Diabetes Mellitusmentioning

confidence: 99%

Suppression of Inflamm-Aging by Moringa oleifera and Zingiber officinale Roscoe in the Prevention of Degenerative Diseases: A Review of Current Evidence

Sahardi

Makpol

2023

Molecules

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Revisiting the protective effects of ginger phenolic compounds on the kidneys: A narrative review

Hoseinzadeh Moghaddam,

Vatankhah,

Armide

et al. 2024

Food and Humanity

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Research progress of ginger in the treatment of gastrointestinal tumors

Chen,

Nan,

Huang

et al. 2023

World J Gastrointest Oncol

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Cancer seriously endangers human health. Gastrointestinal cancer is the most common and major malignant tumor, and its morbidity and mortality are gradually increasing. Although there are effective treatments such as radiotherapy and chemotherapy for gastrointestinal tumors, they are often accompanied by serious side effects. According to the traditional Chinese medicine and food homology theory, many materials are both food and medicine. Moreover, food is just as capable of preventing and treating diseases as medicine. Medicine and food homologous herbs not only have excellent pharmacological effects and activities but also have few side effects. As a typical medicinal herb with both medicinal and edible uses, some components of ginger have been shown to have good efficacy and safety against cancer. A mass of evidence has also shown that ginger has anti-tumor effects on digestive tract cancers (such as gastric cancer, colorectal cancer, liver cancer, laryngeal cancer, and pancreatic cancer) through a variety of pathways. The aim of this study is to investigate the mechanisms of action of the main components of ginger and their potential clinical applications in treating gastrointestinal tumors.

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Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies

Cited by 3 publications

References 58 publications

Suppression of Inflamm-Aging by Moringa oleifera and Zingiber officinale Roscoe in the Prevention of Degenerative Diseases: A Review of Current Evidence

Suppression of Inflamm-Aging by Moringa oleifera and Zingiber officinale Roscoe in the Prevention of Degenerative Diseases: A Review of Current Evidence

Revisiting the protective effects of ginger phenolic compounds on the kidneys: A narrative review

Research progress of ginger in the treatment of gastrointestinal tumors

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