Renovascular disease in children and adolescents

Piercy, K. Todd; Hundley, Jonathan C.; Stafford, Jeanette M.; Craven, Timothy E.; Nagaraj, Shashi; Dean, Richard H.; Hansen, Kimberley J.

doi:10.1016/j.jvs.2005.03.007

Cited by 53 publications

(39 citation statements)

References 29 publications

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“…Revascularization in these patients would be less likely to cure their hypertension, whereas younger hypertensive patients (particularly those <30 years of age) are more likely to have renovascular hypertension that resolves with surgical revascularization. 196,228,266,269 …”

Section: Outcomes Of Surgical Revascularizationmentioning

confidence: 99%

Fibromuscular Dysplasia: State of the Science and Critical Unanswered Questions

Olin¹,

Gornik²,

Bacharach³

et al. 2014

Circulation

395

490

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Section: Outcomes Of Surgical Revascularizationmentioning

confidence: 99%

Fibromuscular Dysplasia: State of the Science and Critical Unanswered Questions

Olin¹,

Gornik²,

Bacharach³

et al. 2014

Circulation

395

490

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“…Reported outcomes in previous studies on revascularization surgeries, such as bypass and autotransplantation, were clinical benefit rates of 81-100% and cure rates of 59-88% [27,28,38]. All of the patients in our study who underwent bypass surgery (n=4) achieved clinical benefit (1 cured, 3 with improved BP).…”

Section: Discussionmentioning

confidence: 56%

Long-Term Outcomes of Pediatric Renovascular Hypertension

Chung

Lee

Park

et al. 2017

Kidney Blood Press Res

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Background/Aims: Renovascular hypertension (RVHT) is an important cause of childhood hypertension. This study evaluated the clinical characteristics and outcomes of Korean children with RVHT. Methods: Children treated for RVHT between 2000 and 2015 at our center were retrospectively reviewed. Results: Forty-six children were followed for a median of 6.5 (0.66-27.23) years. Forty-five percutaneous transluminal angioplasties (PTAs) were performed in 32 children. At the last visit, clinical benefit was observed in 53.3% of children. Patients with comorbid cerebrovascular disease (CVD) showed less favorable long-term outcomes after PTA (clinical benefit in 41.7% vs. 61.1% in others) and higher restenosis rates (50% vs. 31.6% in others). Surgical procedures (bypass or nephrectomy) were performed in 8 patients. After surgery, blood pressure was normalized in 2 patients, improved in 3 patients, and unchanged in the remaining patients. Between PTA group (n=21) and medication group (n=14), percentage of atrophic kidneys became higher after follow-up period in medication group than in PTA group (60.0% vs. 26.1%, P=0.037). Conclusion: Aggressive treatment of pediatric RVHT yielded fair outcomes in our cohort. CVD comorbidity was associated with relatively poor PTA outcomes. To confirm our findings, larger cohort studies with a longer follow-up period are warranted.

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“…These kidneys are then auto-transplanted back to the child [15]. The medium long-term results of surgery are generally quite good, with at least 75% of the children having their high blood pressure cured or improved [14,[16][17][18][19].…”

Section: Surgerymentioning

confidence: 99%

Renal artery stenosis: is angiography still the gold standard in 2011?

Tullus

2011

Pediatr Nephrol

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Renovascular hypertension (RVH) is an unusual cause of hypertension in children that is important to diagnose as it is potentially curable with angioplasty or surgery. Digital subtraction angiography is the gold standard for diagnosing RVH; for other methods like ultrasound, isotope studies, magnetic resonance angiography and computed tomography angiography sensitivity is still too low to reliably exclude RVH. Clinical and laboratory criteria that suggest RVH will be proposed and recommendations when digital subtraction angiography should be performed will be made. A treatment algorithm that suggests when to use medical treatment, interventional radiology and surgery in children with RVH will be given.

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Renovascular disease in children and adolescents

Cited by 53 publications

References 29 publications

Fibromuscular Dysplasia: State of the Science and Critical Unanswered Questions

Fibromuscular Dysplasia: State of the Science and Critical Unanswered Questions

Long-Term Outcomes of Pediatric Renovascular Hypertension

Renal artery stenosis: is angiography still the gold standard in 2011?

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