The COVID-19 pandemic had a serious impact on various aspects of urban areas, such as the economy, public health, and planning, especially campuses. This article analyses the spatial use problems faced by historic universities during the pandemic, including poor dormitory environments, lack of leisure spaces, low utilization of green spaces, and unreasonable cafeteria design. To address these problems, the article proposes some corresponding suggestions. For dormitory buildings, it is recommended to activate the ground floor space for medical purposes during the pandemic and develop other functions in the post-epidemic era. For leisure spaces, the article suggests designing independent characteristic spaces from five perspectives, including park areas, fitness facilities, student activity centers, coffee shops, and libraries, to meet the requirements and different needs during the pandemic. For green spaces on campuses, it is recommended to increase interactive function for students rather than leaving them unengaged oases. For cafeteria renovation, it is suggested to increase space utilization, maintain an appropriate dining distance, create independent quanrantine areas to provide separate or exclusive dining spaces and design personalized spaces to improve diners' sense of security and comfort.