Repair of a unique sinus of Valsalva defect in an infant

Abstract

Sinus of Valsalva aneurysm is a rare disease characterized by the partial elevation of the aortic root. Few reports are available on the surgical treatment for infants. We report the repair of an extremely rare case of a sinus of Valsalva defect with a ventricular septal defect and right ventricular outflow tract stenosis in an infant. It was not a sinus of Valsalva aneurysm, but it exhibited abnormal partial bulging of the aortic root and forming an aneurysm‐like cavity within the right ventricular myocardium. We performed direct closure of the sinus of Valsalva aneurysm‐like cavities and intracardiac repair in two stages. Three years after total repair, the patient remained healthy and asymptomatic.

[Retracted] Study on Inflammatory Factors in Aneurysmal Perimembranous Ventricular Septal Defect in Congenital Heart Disease

“…The formation of true perimembranous aneurysm is due to the failure to close the fetal membranous ventricular septum in time after birth, the closure of the membranous portion is delayed after birth, and part of the generated membranous portion is continuously pressed under the left ventricular high pressure to form perimembranous aneurysm, leaving the top of the tumor, and the breach causes a left-to-right shunt at the ventricular level. Another common perimembranous aneurysm VSD is the so-called pseudoperimembranous aneurysm, which is a relatively immature fibrous tissue formed by the continuous proliferation and adhesion of the tricuspid valve septum, chordae tendineae, or surrounding tissue [7][8][9]. Previous study has shown that under the condition of left-to-right shunting of intraventricular blood at the level of VSD chamber, long-term high pressure impacted the inferior membrane defect, causing damage to the perimembranous tissue and the gap of the true perimembranous aneurysm.…”