Repair of fistulae in-ano in children using image guided Histoacryl injection after failure of conservative treatment

Anorectal Complaints: Hemorrhoids, Fissures, Abscesses, Fistulae

“…Various other approaches to management of pediatric fistula-in-ano have been described. [11][12][13] However, these have not been compared with one another and management decisions do not have a solid basis in published data. Even in adults, management of fistulain-ano is an area of ongoing evolution and debate.…”

Systematic Review of Cyanoacrylate Embolization for Refractory Gastrointestinal Fistulae

“…No complications other than itching of the perianal zone unresponsive to simple analgesia was reported in 2 patients. 30 Postprocedural median follow-up in this cohort of patients with hindgut fistulae was 18 months (range 1-43 months).…”

“…Four prospective studies reporting the outcomes of 92 patients were identified through the electronic search. [27][28][29][30] All fistulae were cryptoglandular in etiology, and were percutaneously approached using Histoacryl or Glubran 2, either alone or in combination with the contrast agent Lipiodol. Cumulative success rate reported in these 4 studies was 84%, ranging from 68% to 95%, and average number of sessions required to achieve closure of the fistulae was 1.2.…”

Histoacryl injection in the management of fourth branchial fistula

“…However, there were several articles that reported on the use of tissue-adhesive materials and glue in adults for tissue approximation and hemostasis in surgery [14]. The mode of action of histoacryl depends on the presence of tissue moisture, which immediately polymerizes into a solid substance with a stable connection to the tissue [4]. The tissue-adhesive histoacryl is composed of enbucrilate; we used it colored with dyestuff D Et violet No 2.…”

“…Our institute has gained experience in histoacryl injection in the management of a perianal fistula, with good results [4]. This led us to extend its use in the management of a neck fistula.…”