Reparative dentine following cavity preparation and fillings in the rat molar

Weider, Stanley R.; Schour, Isaac; Mohammed, Clive I.

doi:10.1016/0030-4220(56)90103-7

Cited by 29 publications

(10 citation statements)

References 4 publications

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“…Calcium hydroxide (Ca(OH) 2 ) and Ca(OH) 2 compounds are the gold standards used to preserve vitality through pulp capping since 1920 [3]. Numerous subsequent studies have demonstrated dentinal bridge formations in about 50% -87% of cases capped with various Ca(OH) 2 formulations [4][5][6]. However, Ca(OH) 2 and their formulations have been known as having a limited effect on pulp tissue repair.…”

Section: Introductionmentioning

confidence: 99%

The inflammatory response of the pulp after direct capping with platelet-rich plasma and enamel matrix derivative: A controlled animal study

Maden¹,

Orhan²,

Ertuğrul³

et al. 2014

OJST

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Aims: To evaluate the inflammatory response of the exposed pulp of incisor teeth in rats after direct pulp capping, using platelet rich plasma (PRP), enamel matrix derivate (EMD), mineral trioxide aggregate (MTA) and calcium hydroxide (Ca(OH) 2). Methods: The study was conducted on 36 Wistar albino rats with a total of 144 incisor teeth. The pulps of 96 teeth of the rats were perforated and capped with different agents. Serving as the positive control group, the pulps of 24 teeth were only perforated and capped without capping agents, whereas the pulps of 24 teeth were used as the negative control group without being perforated (without any process). The research was ended with the extracting of the teeth on the 7th day-28th day. The teeth were taken to the routine and histological follows; cross sections were prepared and painted with hematoxylen & eosin. All of the sections were evaluated in terms of inflammatory reaction by histologic analysis taken by light microscope. Statistical analysis was used. The normal distribution of all data was tested with the Mann Whitney U and the differences between the groups were analyze dusing Kruskal Wallis test at 0.05 level. Results: There are no statistically significant differences in terms of inflammation type and necrosis among the treatment groups on 7 days' post capping. However, improved inflammatory cell accumulation, hyperemia and lowest necrosis were observed from the samples treated with PRP (p < 0.05). Conversely, the EMD group indicated that the criteria of inflammation scores and hyper-emia were higher in the 28th day (p < 0.05). Conclusions: Most of cells accumulating in the PRP group and most necrosis were seen in the EMD group. These new PRP materials might serve as pulp capping biomaterials to induce initial healing response in the future.

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Section: Introductionmentioning

confidence: 99%

The inflammatory response of the pulp after direct capping with platelet-rich plasma and enamel matrix derivative: A controlled animal study

Maden¹,

Orhan²,

Ertuğrul³

et al. 2014

OJST

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“…Neki autori zato patolo{ki dentin smatraju reparatornim tkivom i to naj~e{}e ako se radi o dentinskom mostu koji se formira na eksponiranoj pulpi. 5,8,9 Nasuprot ovome, brojni autori, dentinu koji se lu~i pod dejstvom iritacija prepisuju isklju}ivo patolo{ki karakter. 1,11,4,12,30,29,27 Vojinovi} i sar.…”

Section: Spolja{nji Faktori Koji Uti~u Na Proces Patolo{ke Dentinogenezeunclassified

“…Weider i sar. 8,9 su dokazali da je stvaranje patolo{kog dentina kod dubokog kaviteta u po~etku usporenije, da bi se na kraju ubrzalo.…”

Section: Mehanizam Lu~enja Patolo{kog Dentinaunclassified

“…Nazivi koji su se koristili za dentin izlu~en pod pato-lo{kim okolnostima su brojni i razli~iti. Tako se ovaj dentin prvobitno ozna~avao kao "patolo{ki", a zatim kao "reparatorni dentin" 1,2,3,4,5,6,7,8,9 medjutim, naj~e{}e se u savremenoj literaturi koristi naziv "tercijarni dentin". 10,11,12,13,14,15,16 Linde 17 smatra da se "tercijarni" ili "reparativni" dentin formira kao odgovor na traumu pulpe.…”

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Pathological dentinogenesis in posteruptiv toot development

Vojinović¹,

Stevanovic²

2004

Stomatol. glas. Srb.

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“…Schour and Massler [22] have stated that human and rat molars are similar histologically and physiologically, as well as in form and function. In a number of histological studies, the rat molar has been used as a test object and analyzed for its reactions to various medicaments and experimental conditions [22][23][24]. At this time, the rat molar is the preferred biologic test object because of its established similarities to the human molar and its availability in large numbers, and because it can be studied under controlled conditions.…”

Section: Introductionmentioning

confidence: 99%

Characterization of the dental pulp using optical coherence tomography

et al. 2006

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The inner structure of teeth, i.e. the root canal anatomy, is very complex. However a good knowledge of endodontic architecture is the first step towards successful endodontic treatment. Optical coherence tomography (OCT) is a powerful technique to generate images of hard and soft tissue. Its images show dependency on the optical properties of the tissue under analysis. Changes in the scattering and absorption of tissues can be observed through the OCT images. In this work, we used optical coherence tomography to perform in vitro studies of the inner structure of the first molar of albino rats (Rattus norvegicus). Focusing on the pulp chamber and in the root canal, we compare the images generated with the OCT technique to the histology. We are analyzing the feasibility of OCT to help on the diagnostic of endodontic diseases.

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Reparative dentine following cavity preparation and fillings in the rat molar

Cited by 29 publications

References 4 publications

The inflammatory response of the pulp after direct capping with platelet-rich plasma and enamel matrix derivative: A controlled animal study

The inflammatory response of the pulp after direct capping with platelet-rich plasma and enamel matrix derivative: A controlled animal study

Pathological dentinogenesis in posteruptiv toot development

Characterization of the dental pulp using optical coherence tomography

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