Repeat MitraClip Therapy for Significant Recurrent Mitral Regurgitation in High Surgical Risk Patients

Kreidel, Felix; Frerker, Christian; Schlüter, Michael; Alessandrini, Hannes; Tourdias, Thomas; Geidel, Stephan; Schäfer, Ulrich; Kück, Karl‐Heinz

doi:10.1016/j.jcin.2015.06.019

Cited by 49 publications

(49 citation statements)

References 16 publications

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“…A previous study by Kreidel et al found worse results after ReClip when LLI was the cause of recurrent MR . Interestingly, this association was not observed in our cohort, which may be due to different methods applied to define LLI.…”

Section: Discussionmentioning

confidence: 99%

“…Interestingly, this association was not observed in our cohort, which may be due to different methods applied to define LLI. While leaflet insertion was measured in a TOE LVOT view, the plane aligned just next to the clip in our study, Kreidel et al calculated LLI based on measurements taken from transthoracic echocardiograms performed before and after the first procedure . In our opinion, these calculations may be inaccurate, as it presumes that all measurements are taken in the same plane.…”

Section: Discussionmentioning

confidence: 99%

“…Although this matter has been commented on in several trials and registry studies, published literature is mainly limited to case reports . Kreidel et al published a small series, but included patients irrespective of the initial result of the first procedure …”

Section: Introductionmentioning

confidence: 90%

See 2 more Smart Citations

Repeated MitraClip procedure in patients with recurrent MR after a successful first procedure: Limitations and outcome

Curio

Reinthaler

Kasner

et al. 2017

J Interven Cardiology

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Repeated MitraClip procedure in patients with recurrent MR after a successful first procedure: Limitations and outcome

Curio

Reinthaler

Kasner

et al. 2017

J Interven Cardiology

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show abstract

“…In 21 patients treated with repeat MitraClip intervention for recurrent MR, Kreidel et al [10] showed that procedural success was suboptimal (62%), especially in patients with a loss of leaflet insertion due to MV leaflet tearing or perforation. Mortality in patients successfully treated was relevant (62%) at a median follow-up of 8.5 months.…”

Section: Strategies To Address Mitraclip Failurementioning

confidence: 99%

“…Real-world registries, which generally include more patients with functional MR, also show that rates of MitraClip failure are not negligible [3] and that residual or relapsing severe MR is a strong prognostic determinant [4,5]. In light of the above, reintervention after failed MitraClip therapy is increasingly performed as a strategy to overcome the negative prognostic impact of untreated MR (Table 1) [2,6,7,8,9,10]. Different surgical and percutaneous approaches have been adopted in this context, but literature on this topic is scant.…”

Section: Introductionmentioning

confidence: 99%

Strategies and Outcomes of Repeat Mitral Valve Interventions after Failed MitraClip Therapy

Grasso

Buccheri²,

Capodanno³

et al. 2017

Cardiology

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Percutaneous mitral valve repair (PMVR) with the MitraClip system (Abbott Vascular, Santa Clara, CA, USA) is a valid therapeutic option for patients with severe mitral regurgitation (MR) deemed to be at high or prohibitive surgical risk. Despite the reassuring data on efficacy and long-term durability of the procedure, the proportion of patients with residual or relapsing severe MR after MitraClip therapy is not negligible. In light of the detrimental prognostic impact of severe MR, repeat interventions are increasingly performed in clinical practice using different techniques. In high-risk settings, percutaneous procedures have proven to be effective and safe at reducing MR. Building on this, we sought to summarize the current landscape and clinical experience of reinterventions after failed MitraClip therapy, so as to assist physicians facing the clinical hurdle of proper treatment management after failed PMVR.

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Repeat MitraClip for early recurrent mitral regurgitation

Hachinohe

Latib²,

Agricola

et al. 2017

Cathet Cardio Intervent

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Treatment for recurrent mitral regurgitation (MR) after MitraClip therapy remains a challenging issue. This study reports the efficacy of repeat MitraClip therapy for recurrent MR during the early phase after the index MitraClip procedure. We present a case series of four consecutive patients who underwent repeat MitraClip procedures for severe recurrent MR during the early phase. Partial clip detachment (PCD) was the suspected cause of recurrent MR in these cases. All patients received additional clip(s). PCD could be stabilized and MR grade improved in all cases compared with that before the second procedure. Repeat MitraClip procedures for recurrent MR due to PCD are feasible during the early phase. However, patients having PCD with paracommissural MR may not be good candidates for repeat MitraClip.

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Repeat MitraClip Therapy for Significant Recurrent Mitral Regurgitation in High Surgical Risk Patients

Cited by 49 publications

References 16 publications

Repeated MitraClip procedure in patients with recurrent MR after a successful first procedure: Limitations and outcome

Repeated MitraClip procedure in patients with recurrent MR after a successful first procedure: Limitations and outcome

Strategies and Outcomes of Repeat Mitral Valve Interventions after Failed MitraClip Therapy

Repeat MitraClip for early recurrent mitral regurgitation

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