Repeatability of Aerobic Capacity Measurements in Parkinson Disease

Katzel, Leslie I.; Sorkin, John D.; Macko, Richard F.; Smith, Barbara A.; Ivey, Frederick M.; Shulman, Lisa M.

doi:10.1249/mss.0b013e31822432d4

Cited by 39 publications

(30 citation statements)

References 21 publications

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“…The results of this study are similar to recent finding of aerobic capacity in PWP [42]. Katzel and colleagues demonstrated generally high test-retest reliability, however a significant between test session, 0.56 mL/mg/min, difference was noted in VO 2 peak measurements [42]. Further, almost half of the PWP, failed to improve on the second administration of the maximal test (95% CI of −3.5–4.6 mL/mg/min) [42].…”

Section: Discussionsupporting

confidence: 93%

Reliability in One-Repetition Maximum Performance in People with Parkinson's Disease

Buckley

Hass

2012

Parkinson's Disease

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Strength training is an effective modality to improve muscular strength and functional performance in people with Parkinson's disease (PWP). One-repetition maximum (1-RM) is the gold standard assessment of strength; however, PWP suffer from day-to-day variations in symptom severity and performance characteristics, potentially adversely affecting the reliability of 1-RM performance. Herein, we assessed the reliability of 1-RM in PWP. Forty-six participants completed two sessions of 1-RM testing of knee extension, knee flexion, chest press, and biceps curl at least 72 hours apart. Significantly differences between testing sessions were identified for knee extension (P < 0.001), knee flexion (P = 0.042), and biceps curl (P = 0.001); however, high reliability (ICC > 0.90) was also identified between sessions. Interestingly, almost third of subjects failed to perform better on the second testing session. These findings suggest that 1-RM testing can be safely performed in PWP and that disease-related daily variability may influence 1-RM performance.

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Section: Discussionsupporting

confidence: 93%

Reliability in One-Repetition Maximum Performance in People with Parkinson's Disease

Buckley

Hass

2012

Parkinson's Disease

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“…Indeed, although all subjects in the present investigation achieved maximal effort as outlined by the American Thoracic Society,(3) it is possible there was inherent variability in the effort deconditioned subjects were willing to exert from day to day. (21) To this end, there were variations in HR between tests, suggesting inconsistency of effort. Third, there is also considerable technical variation in when VO 2 max occurs depending on how many breaths occur during the sampling period (30s for the present investigation).…”

Section: Discussionmentioning

confidence: 95%

“…We did not conduct a third CPET; however, based on previous literature an additional test is unlikely to provide clinically relevant changes. (8, 13, 21)…”

Section: Discussionmentioning

confidence: 99%

Reliability of Maximal Cardiopulmonary Exercise Testing in Men with Prostate Cancer

Scott

Hornsby

Lane

et al. 2015

Medicine &Amp; Science in Sports &Amp; Exercise

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Purpose In order to accurately assess exercise interventions and to evaluate acute and chronic cardiovascular effects in patients with early-stage cancer, consistently reliable functional outcome measures must be obtained. An incremental cardiopulmonary exercise test (CPET) with gas exchange measurement, to assess peak oxygen consumption (peak VO2), provides the gold standard outcome of cardiorespiratory fitness. Methods In the context of a randomized controlled trial, 40 prostate cancer patients (mean age 59±7 years) following radical prostatectomy performed two maximal CPETs within 5.6±5.5 days of each other. Incremental treadmill tests were performed in the morning under identical laboratory conditions. Reliability and within subject variability from test 1 to test 2 for peak and submaximal variables were assessed by correlation coefficients, intraclass correlations (ICC), Bland-Altman plots, coefficient of variation (CV), and paired t-tests. Results There was high reliability between CPETs for peak VO2 (r=0.92, p<0.001, ICC=0.900); ventilatory threshold (VT; r=0.88, p<0.001, ICC=0.927); minute ventilation-carbon dioxide production relationship (VE/VCO2; r=0.86, p < 0.001, ICC=0.850); and peak heart rate (HR; r=0.95, p<0.001, ICC=0.944). However, high within-subject variability was observed for all CPET parameters (mean coefficient of variation: 4.7%). Compared to test 1, significantly higher mean values were observed for peak VO2 (27.0±5.6 vs. 28.1±5.3 mL·kg·−1min−1, p<0.05), VT (1.91±0.5 vs. 1.97±0.4 L.min−1, p<0.05) and VE/VCO2: (31.3±5.8 vs. 32.8±3.4, p<0.05) in test 2. Conclusion These findings indicate the presence of significant, and potentially clinically important, variability in CPET procedures in men with clinically-localized prostate cancer, and have important implications for the application and utility of CPETs to evaluate the efficacy of interventions to improve aerobic capacity in the oncology setting.

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“…Both aerobic exercise (between 40 and 60% HRres, 3-4 times per week, 30 min per session) and strength training (2-3 times per week, 40-80% of 1RM) appear to result in improved motor function in PD patients [42]; these types of exercise also appear to improve the quality of life in individuals with PD [43,44]. However, strength training appears to be of greater benefit to patients with the disease.…”

Section: Mental Disorders and Neurodegenerative Disordersmentioning

confidence: 99%

Neuroscience of Exercise: From Neurobiology Mechanisms to Mental Health

Portugal¹,

Cevada²,

et al. 2013

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The neuroscience of exercise is a growing research area that is dedicated to furthering our understanding of the effects that exercise has on mental health and athletic performance. The present study examined three specific topics: (1) the relationship between exercise and mental disorders (e.g. major depressive disorder, dementia and Parkinson's disease), (2) the effects of exercise on the mood and mental health of athletes, and (3) the possible neurobiological mechanisms that mediate the effects of exercise. Positive responses to regular physical exercise, such as enhanced functional capacity, increased autonomy and improved self-esteem, are frequently described in the recent literature, and these responses are all good reasons for recommending regular exercise. In addition, physical exercise may improve both mood and adherence to an exercise program in healthy individuals and might modulate both the performance and mental health of athletes. Exercise is associated with the increased synthesis and release of both neurotransmitters and neurotrophic factors, and these increases may be associated with neurogenesis, angiogenesis and neuroplasticity. This review is a call-to-action that urges researchers to consider the importance of understanding the neuroscience of physical exercise and its contributions to sports science.

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Repeatability of Aerobic Capacity Measurements in Parkinson Disease

Cited by 39 publications

References 21 publications

Reliability in One-Repetition Maximum Performance in People with Parkinson's Disease

Reliability in One-Repetition Maximum Performance in People with Parkinson's Disease

Reliability of Maximal Cardiopulmonary Exercise Testing in Men with Prostate Cancer

Neuroscience of Exercise: From Neurobiology Mechanisms to Mental Health

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