The CO2CRC Otway Project conducted under the Australian Cooperative Research Centre for Greenhouse Gas Technologies is the first of its kind, where [Formula: see text] is injected into a depleted gas reservoir. The use of depleted gas fields for [Formula: see text] storage and or enhanced gas recovery is likely to become globally adopted. Therefore, the CO2CRC project provides important experience for monitoring under these conditions. However, injection of [Formula: see text] into a depleted gas reservoir (residual gas saturation zone in this case) does not present a favorable condition for the application of geophysical monitoring techniques, and particularly seismic methods.