Repeated Daily Exposure to Direct Current Stimulation Does Not Result in Sustained or Notable Side Effects

Richmond, Lauren L.; Wolk, David A.; Coslett, H. Branch; Vyas, Govinda; Olson, Ingrid R.

doi:10.1016/j.brs.2013.06.003

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…On the other hand, repeated daily tDCS with a current density of about 0.06 mA/cm 2 (e.g. if the stimulus electrode is 25–35 cm 2 , current is 1.5–2.1 mA as in the standard protocols) caused clinically significant skin irritation under the electrodes in some patients (Nitsche et al, 2008) though not in all studies (Richmond et al, 2013). Actually, as shown in Table 1, persistent skin lesions under the electrodes have been reported by several authors (Palm et al, 2008, Frank et al, 2010, Kasahara et al, 2011, Riedel et al, 2012, Rodríguez et al, 2014, Wang et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Adverse events of tDCS and tACS: A review

Matsumoto

Ugawa

2017

Clinical Neurophysiology Practice

265

160

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Section: Introductionmentioning

confidence: 99%

Adverse events of tDCS and tACS: A review

Matsumoto

Ugawa

2017

Clinical Neurophysiology Practice

265

160

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show abstract

Study design and methodology for a multicentre, randomised controlled trial of transcranial direct current stimulation as a treatment for unipolar and bipolar depression

Alonzo

Aaronson

Bikson

et al. 2016

Contemporary Clinical Trials

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Transcranial Direct Current Stimulation Enhances Verbal Working Memory Training Performance over Time and Near Transfer Outcomes

Richmond

Wolk

Chein

et al. 2014

Journal of Cognitive Neuroscience

128

101

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Studies attempting to increase working memory (WM) capacity show promise in enhancing related cognitive functions but have also raised criticism in the broader scientific community given the inconsistent findings produced by these studies. Transcranial direct current stimulation (tDCS) has been shown to enhance WM performance in a single session [Fregni, F., Boggio, P., Nitsche, M., Bermpohl, F., Anatal, A., Feredoes, E., et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Experimental Brain Research, 166, 23–30, 2005]; however, the extent to which tDCS might enhance learning on a WM training regime and the extent to which learning gains might transfer outside the training task remains largely unknown. To this end, participants engaged in an adaptive WM training task [previously utilized in Richmond, L., Morrison, A., Chein, J., & Olson, I. Working memory training and transfer in older adults. Psychology & Aging, 26, 813–822, 2011; Chein, J., & Morrison, A. Expanding the mind's workspace: Training and transfer effects with a complex working memory span task. Psychonomic Bulletin & Review, 17, 193–199, 2010] for 10 sessions over 2 weeks, concurrent with either active or sham stimulation of dorsolateral pFC. Before and after training, a battery of tests tapping domains known to relate to WM abilities was administered. Results show that tDCS enhanced learning on the verbal portion of the training task by 3.65 items. Furthermore, tDCS was shown to enhance near transfer to other untrained WM tasks in comparison with a no-contact control group. These results lend support to the idea that tDCS might bolster training and transfer gains in populations with compromised WM abilities.

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Repeated Daily Exposure to Direct Current Stimulation Does Not Result in Sustained or Notable Side Effects

Cited by 3 publications

References 8 publications

Adverse events of tDCS and tACS: A review

Adverse events of tDCS and tACS: A review

Study design and methodology for a multicentre, randomised controlled trial of transcranial direct current stimulation as a treatment for unipolar and bipolar depression

Transcranial Direct Current Stimulation Enhances Verbal Working Memory Training Performance over Time and Near Transfer Outcomes

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