2023
DOI: 10.21203/rs.3.rs-3064324/v1
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Repeated Mild Traumatic Brain Injury Causes Sex-specific Increases in Cell Proliferation and Inflammation in Juvenile Rats

Abstract: Childhood represents a period of significant growth and maturation for the brain, and is also associated with a heightened risk for mild traumatic brain injuries (mTBI). There is also concern that repeated-mTBI (r-mTBI) may have a long-term impact on developmental trajectories. Using an awake closed head injury (ACHI) model, that uses rapid head acceleration to induce a mTBI, we investigated the acute effects of repeated mTBI (r-mTBI) on neurological function and cellular proliferation in juvenile male and fem… Show more

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