2018
DOI: 10.1080/01902148.2018.1517837
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Repeated pulmonary exposures to zinc ions enhance inflammatory responses to subsequent metal exposures

Abstract: Aim of study: Metal contaminants contribute to adverse human health effects via acute and chronic exposures. Acute metal exposures followed by prolonged secondary metal exposures may elicit exaggerated inflammatory responses in certain individuals. The aim of this study is to determine whether repeated pulmonary exposures to zinc chloride (ZnCl2) alters subsequent responses to zinc or cerium exposures. Materials and Methods: Rats were intratracheally (IT) instilled with physiologic saline (n=24) or 0.05 mg/k… Show more

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