RepeatModeler and RepeatMasker output files

Nowell, Reuben; Wilson, Christopher; Almeida, Pedro; Schiffer, Philipp; Fontaneto, Diego; Becks, Lutz; Rodriguez, Fernando; Arkhipova, Irina; Barraclough, Timothy

doi:10.5061/dryad.fbg79cnsr

Cited by 2 publications

References 2 publications

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Evolutionary dynamics of transposable elements in bdelloid rotifers

Nowell

Wilson

Almeida

et al. 2020

Preprint

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Transposable elements (TEs) are selfish genomic parasites whose ability to spread autonomously is facilitated by sexual reproduction in their hosts. If hosts become obligately asexual, TE frequencies and dynamics are predicted to change dramatically, but the long-term outcome is unclear. Here, we test current theory using whole-genome sequence data from eight species of bdelloid rotifers, a class of invertebrates where males are thus far unknown. Contrary to expectations, we find a diverse range of active TEs in bdelloid genomes, at an overall frequency within the range seen in sexual species. We find no evidence that TEs are spread by cryptic recombination or restrained by unusual DNA repair mechanisms, but we report that bdelloids share a large and unusual expansion of genes involved in RNAi-mediated TE suppression. This suggests that enhanced cellular defence mechanisms might mitigate the deleterious effects of active TEs and compensate for the consequences of long-term asexuality.

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Evolutionary dynamics of transposable elements in bdelloid rotifers

Nowell

Wilson

Almeida

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

Evolutionary dynamics of transposable elements in bdelloid rotifers

Nowell

Wilson

Almeida

et al. 2021

eLife

Self Cite

View full text Add to dashboard Cite

Transposable elements (TEs) are selfish genomic parasites whose ability to spread autonomously is facilitated by sexual reproduction in their hosts. If hosts become obligately asexual, TE frequencies and dynamics are predicted to change dramatically, but the long-term outcome is unclear. Here, we test current theory using whole-genome sequence data from eight species of bdelloid rotifers, a class of invertebrates in which males are thus far unknown. Contrary to expectations, we find a variety of active TEs in bdelloid genomes, at an overall frequency within the range seen in sexual species. We find no evidence that TEs are spread by cryptic recombination or restrained by unusual DNA repair mechanisms. Instead, we find that that TE content evolves relatively slowly in bdelloids and that gene families involved in RNAi-mediated TE suppression have undergone significant expansion, which might mitigate the deleterious effects of active TEs and compensate for the consequences of long-term asexuality.

show abstract

RepeatModeler and RepeatMasker output files

Cited by 2 publications

References 2 publications

Evolutionary dynamics of transposable elements in bdelloid rotifers

Evolutionary dynamics of transposable elements in bdelloid rotifers

Evolutionary dynamics of transposable elements in bdelloid rotifers

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