Repellency property of long chain aliphatic methyl ketones against &lt;i&gt;Anopheles gambiae&lt;/i&gt; s.s

Innocent, Ester; Gikonyo, N. K.; Nkunya, Mayunga H.H.

doi:10.4314/thrb.v10i1.14342

Cited by 34 publications

(22 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Amongst the compounds isolated in F. thonningii essential oils is the C-15 compound; 6, 10, 14 trimethyl-2-pentadecanone an aliphatic methyl ketone which has been reported to possess insect repellent properties. The repellent properties of 6, 10, 14 trimethyl-2-pentadecanone at a concentration of 10 % (w/v), were comparable to those of the commercial repellent, N, N diethyl-m-toluamide (DEET) (Innocent, 2008).…”

Section: Antiprotozoal Propertiesmentioning

confidence: 80%

“…A study carried out to evaluate the antiplasmodial activity of F. thonningii against Plasmodium falciparum the protozoan parasite that causes malaria reported no significant antiplasmodial activity (Jansen et al, 2010). F. thonningii possibly just possesses good insect repellent properties and hence reduces the contact of the vector with humans, minimising incidence of malaria transmission (Jansen et al, 2010;Innocent, 2008). Amongst the compounds isolated in F. thonningii essential oils is the C-15 compound; 6, 10, 14 trimethyl-2-pentadecanone an aliphatic methyl ketone which has been reported to possess insect repellent properties.…”

Section: Antiprotozoal Propertiesmentioning

confidence: 99%

See 1 more Smart Citation

Phytochemistry, pharmacology and ethnomedicinal uses of Ficus thonningii (Blume moraceae): A review

Dangarembizi¹,

Erlwanger²,

Moyo³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

View full text Add to dashboard Cite

The common wild fig, Ficus thonningii, is extensively used in African ethnomedicine for treating a number of disease conditions which include diarrhoea, urinary tract infections, diabetes mellitus, gonorrhoea, respiratory infections, and mental illnesses. This review aims to present a logical analysis of the nutritional, phytochemical and pharmacological properties of F. thonningii in relation to its therapeutic applications. A bibliographic analysis of the uses, phytochemical constituents and phytophamacological properties of Ficus thonningii was carried out using published papers, medicinal plant databases and various ethnobotanical and ethnopharmacological books. Ficus thonningii contains various bioactive compounds which include alkaloids, terpenoids, flavonoids, tannins and active proteins, all of which contribute to its curative properties. In vitro and in vivo pharmacological studies revealed that F. thonningii possesses antimicrobial, antidiarrhoeal, antihelmintic, antioxidant, anti-inflammatory and analgesic properties. Acute and sub-chronic toxicity studies have shown that Ficus thonningii is non-toxic if administered orally in low doses. Scientific research has validated the ethnomedicinal claims that Ficus thonningii is useful in disease management. However, there is need to continue identifying, isolating and quantifying the active principles and possibly determine the mechanisms underlying its curative properties.

show abstract

Section: Antiprotozoal Propertiesmentioning

confidence: 80%

Section: Antiprotozoal Propertiesmentioning

confidence: 99%

Phytochemistry, pharmacology and ethnomedicinal uses of Ficus thonningii (Blume moraceae): A review

Dangarembizi¹,

Erlwanger²,

Moyo³

et al. 2013

Afr. J. Trad. Compl. Alt. Med.

View full text Add to dashboard Cite

show abstract

“…Studies showed that the compound was more persistent than the EPA-registered active ingredient in BioUD , 2-undecanone, in laboratory choice bioassays on filter paper against two species of ticks. Innocent et al (2008) also found 2-tridecanone to be more effective than 2-undecanone as a mosquito repellent. In the current study, 2-tridecanone was a persistent repellent on cotton cloth.…”

Section: Discussionmentioning

confidence: 91%

“…More recently, unformulated 2-tridecanone was found to be a more effective repellent than 2-undecanone against mosquitoes (Innocent et al, 2008). Similar comparative studies have not been conducted with ticks, and no published studies on the tick repellency of 2-tridecanone are currently available.…”

Section: Introductionmentioning

confidence: 96%

First report of the repellency of 2-tridecanone against ticks

Kimps

Bissinger

Apperson

et al. 2010

Medical and Veterinary Entomology

View full text Add to dashboard Cite

2-Tridecanone and 2-undecanone are both found naturally in the trichomes of wild tomato plants and are important in plant resistance to herbivory. 2-Undecanone is the U.S. Environmental Protection Agency (EPA)-registered active ingredient in the commercially available arthropod repellent, BioUD(®) . The goal of this study was to examine the tick repellency of 2-tridecanone. Two-choice bioassays were conducted using 8% 2-tridecanone vs. the repellent carrier (absolute ethanol) and compared with two-choice studies using 8% 2-undecanone vs. absolute ethanol. Unfed, host-seeking adult (mixed sex) Amblyomma americanum (L.) (Acari: Ixodidae) and Dermacentor variabilis Say (Acari: Ixodidae) were used to evaluate repellency and time to repellent failure at room temperature. The present study shows in filter paper assays (0.63 mg test compound/cm(2) ) that 2-tridecanone was 87% repellent to A. americanum at 12 h after application, but had no statistically significant repellency at 15 h and 24 h, and was 72% repellent to D. variabilis at 15 h, but had no statistically significant repellency at 24 h. By contrast, 2-undecanone was 74% and 75% repellent to A. americanum and D. variabilis, respectively, at 2 h after application, but no statistically significant repellency was noted at 2.5 h and 3 h. In two-choice assays on cheesecloth, 2-tridecanone at 0.25 mg/cm(2) was 85% repellent to A. americanum 6 h after application, demonstrating its potential use as an arthropod repellent that can be used on clothing without the need for formulation. No statistically significant repellency was found at 9 h or 12 h. The potential use of 2-tridecanone as a tick repellent is discussed.

show abstract

“…Hexahydroxyfarnesylacetone (6,10,14-trimethyl-2-pentadecanone) may repel insects, while according to some studies aliphatic methyl ketones with long chains exert such activity (Innocent et al 2008). Also, identified aliphatic alcohols including 2-nonen-1-ol, 2-tetradecen-1-ol, 7-tetradecen-1-ol, and 2-hexyl-1-decanol are common components of essential oils extracted from different plants and for which antimicrobial activity was demonstrated (Manilal et al 2009;Ü çüncü et al 2010;Ogunlesi et al 2010;Rahmat et al 2006).…”

Section: Resultsmentioning

confidence: 99%

Comparative study on the essential oils of Myosotis arvensis and Myosotis palustris herbs (Boraginaceae)

et al. 2014

View full text Add to dashboard Cite

The essential oils were obtained from Myosotis arvensis L. and M. palustris L. by hydrodistillation and subsequently analyzed by GC-MS. Fifteen components in M. arvensis and twenty-one in M. palustris representing, respectively, 89.63 and 93.19 % of the total oils were identified on the basis of their retention time, mass spectra characteristics and semi-quantitative data were obtained from relative peak area percentages. The 3-methyl-benzaldehyde was found to be the major constituent of both tested oils (42.76 % in M. arvensis and 45.80 % in M. palustris). Additionally, methyl salicylate was a characteristic compound for M. arvensis and a-bisabolol oxide B for M. palustris.

show abstract

Repellency property of long chain aliphatic methyl ketones against <i>Anopheles gambiae</i> s.s

Cited by 34 publications

References 11 publications

Phytochemistry, pharmacology and ethnomedicinal uses of Ficus thonningii (Blume moraceae): A review

Phytochemistry, pharmacology and ethnomedicinal uses of Ficus thonningii (Blume moraceae): A review

First report of the repellency of 2-tridecanone against ticks

Comparative study on the essential oils of Myosotis arvensis and Myosotis palustris herbs (Boraginaceae)

Contact Info

Product

Resources

About